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Developing 3D Organized Human Cardiac Tissue within a Microfluidic Platform
 

Developing 3D Organized Human Cardiac Tissue within a Microfluidic Platform

Article DOI: 10.3791/62539-v
June 15th, 2021

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Summary June 15th, 2021

The goal of this protocol is to explain and demonstrate the development of a three-dimensional (3D) microfluidic model of highly aligned human cardiac tissue, composed of stem cell-derived cardiomyocytes co-cultured with cardiac fibroblasts (CFs) within a biomimetic, collagen-based hydrogel, for applications in cardiac tissue engineering, drug screening, and disease modeling.

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