In the present protocol, we demonstrate how to visualize DNA double-strand end resection during S/G2 phase of the cell cycle using an immunofluorescence-based method.
O'Sullivan, J., Mersaoui, S. Y., Poirier, G., Masson, J. Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging. J. Vis. Exp. (170), e62553, doi:10.3791/62553 (2021).