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Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat
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JoVE Journal Neuroscience
Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

DOI:
10.3791/62596-v

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12:41 min

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August 28, 2021

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, , , , ,
1Dartmouth-Hitchcock Medical Center, 2Geisel School of Medicine at Dartmouth, 3National Institute on Drug Abuse,National Institutes of Health, 4University of Guelph

Chapters

  • 00:06Introduction
  • 01:19Phase 1 Anesthesia: Animal Induction and Preparation
  • 03:38Phase 2 Anesthesia: Animal Setup
  • 07:03Phase 3 Anesthesia: Anatomical Scan Acquisition
  • 08:38Phase 4 Anesthesia: Resting‐State Scan Acquisition
  • 09:44Post‐Scan Recovery
  • 10:25Representative Results: Independent Component Analysis
  • 11:35Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes a method for obtaining stable resting-state functional magnetic resonance imaging (rs-fMRI) data from a rat using low dose isoflurane in combination with low dose dexmedetomidine.

Tags

Keywords: Resting-state FMRIRatAnimal PreparationAnesthesiaDexmedetomidineIsofluranePhysiological MonitoringData Acquisition

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