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Journal / Medicine / Retinale Pigmentepitheltransplantation in einem…
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JoVE Journal Medicine
Retinale Pigmentepitheltransplantation in einem nicht-menschlichen Primatenmodell für degenerative Netzhauterkrankungen
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Retinale Pigmentepitheltransplantation in einem nicht-menschlichen Primatenmodell für degenerative Netzhauterkrankungen

Article DOI: 10.3791/62638-v • 11:20 min • June 14th, 2021
June 14th, 2021 •
*1,2, *1,3,4, 1, 2, 1,2,5, 1,4,6, 1,2,4, 1,2,3,4, 1,7,8
1Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 2Department of Ophthalmology, National University Hospital, Singapore, 3Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 4Singapore Eye Research Institute (SERI), 5UCL Institute of Ophthalmology, 6Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, 7Macula Center Saar, Eye Clinic Sulzbach, Knappschaft Hospital Saar, 8Department of Ophthalmology, University of Bonn
* These authors contributed equally

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Der nicht-menschliche Primat (NHP) ist aufgrund der anatomischen und genetischen Ähnlichkeiten ein ideales Modell für die Untersuchung der zellulären Therapeutika der menschlichen Netzhaut. Dieses Manuskript beschreibt eine Methode zur submakulären Transplantation von retinalen Pigmentepithelzellen im NHP-Auge und Strategien zur Verhinderung intraoperativer Komplikationen im Zusammenhang mit der Makulamanipulation.

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Medizin Heft 172
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