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A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish
 

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Article DOI: 10.3791/62709-v
May 31st, 2021

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Summary May 31st, 2021

We modified the Marmarou weight drop model for adult zebrafish to examine a breadth of pathologies following blunt-force traumatic brain injury (TBI) and the mechanisms underlying subsequent neuronal regeneration. This blunt-force TBI model is scalable, induces a mild, moderate, or severe TBI, and recapitulates injury heterogeneity observed in human TBI.

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