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Journal / Biology / Svansvenens transsektionsblödningsmodell i helt…
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Svansvenens transsektionsblödningsmodell i helt sövda hemofili A-möss
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Svansvenens transsektionsblödningsmodell i helt sövda hemofili A-möss

Article DOI: 10.3791/62952-v • 08:13 min • September 30th, 2021
September 30th, 2021 •
1,2, 1, 1, 3, 1, 4, 5, 1, 6, 1
1Global Drug Discovery, Novo Nordisk A/S, 2Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 3Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 4Independent consultant, 5Catalyst Biosciences, 6Værløse Dyreklinik

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Den raffinerade svansvenstranssektionstranssektionsmodellen (TVT) hos sövda möss är en känslig in vivo-metod för bedömning av hemofil blödning. Denna optimerade TVT-blödningsmodell använder blodförlust och blödningstid som slutpunkter, förfinar andra modeller och undviker döden som slutpunkt.

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Biologi utgåva 175 svansvenstranssektionsmodell svansblödning djurmodell farmakologisk intervention hemofili faktor FVIII slår ut möss
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