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Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)
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JoVE Journal Neuroscience
Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)

Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)

DOI:
10.3791/63150-v

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06:30 min

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December 16, 2021

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, , , , , , ,
1Department of Neurosurgery,Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, and Humboldt-Universität zu Berlin, and Berlin Institute of Health, 2Department of Experimental Neurology and Center for Stroke Research Berlin,Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 3NeuroCure Cluster of Excellence and Charité Core Facility 7T Experimental MRIs,Charité – Universitätsmedizin Berlin

Chapters

  • 00:04Introduction
  • 00:32Animal Preparation
  • 01:05Subarachnoid Hemorrhage (SAH) Induction
  • 04:05MRI Measurement
  • 04:44Results: SAH Bleeding Grade, Bleeding Volume and MRI Images After Endovascular Filament Perforation in Mouse
  • 05:47Conclusion

Summary

Automatic Translation

Automatic Translation

Here we present a standardized SAH mouse model, induced by endovascular filament perforation, combined with magnetic resonance imaging (MRI) 24 h after operation to ensure the correct bleeding site and exclude other relevant intracranial pathologies.

Tags

Keywords: Endovascular Perforation ModelSubarachnoid HemorrhageMagnetic Resonance Imaging (MRI)MouseCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryProlene FilamentACA-MCA BifurcationSubarachnoid Space

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