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Biology

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基于结构的转录因子蛋白沿DNA从原子级步进到粗晶扩散运动的模拟和采样
 
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基于结构的转录因子蛋白沿DNA从原子级步进到粗晶扩散运动的模拟和采样

Article DOI: 10.3791/63406-v 09:17 min March 1st, 2022
March 1st, 2022

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Summary

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该协议的目标是揭示蛋白质沿DNA的一维扩散的结构动力学,使用植物转录因子WRKY结构域蛋白作为示例系统。为此,已经实施了原子和粗粒度分子动力学模拟以及广泛的计算采样。

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生物学, 第181期,
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