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Journal / Immunology and Infection / Crohn Hastalığında Mekanik Stresin Patojenik…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Crohn Hastalığında Mekanik Stresin Patojenik Rolünü İncelemek için TNBS Kaynaklı Bir Kemirgen Modeli
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Crohn Hastalığında Mekanik Stresin Patojenik Rolünü İncelemek için TNBS Kaynaklı Bir Kemirgen Modeli

Article DOI: 10.3791/63499-v • 05:08 min • March 1st, 2022
March 1st, 2022 •
*1, *1, *1, 2, 1
1Department of Internal Medicine, the University of Texas Medical Branch, 2Department of Pathology, the University of Texas Medical Branch
* These authors contributed equally

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Mevcut protokol, kemirgenlerde Crohn benzeri bir kolit modelinin gelişimini açıklamaktadır. Transmural inflamasyon TNBS damlatma bölgesinde darlığa yol açar ve darlığa yakın segmentte mekanik genişleme gözlenir. Bu değişiklikler kolitte mekanik stresin incelenmesine izin verir.

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İmmünoloji ve Enfeksiyon Sayı 181
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