Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Asli  Pinar Zorba Yildiz; Hakan Darici; Burcak Yavuz; Emrah Sefik Abamor; Ceren Ozdemir; Muge Elif Yasin; Melahat Bagirova; Adil Allahverdiyev; Erdal Karaoz

doi:10.3791/63622

Journal

/

Bioengineering

/

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

JoVE Journal
Bioengineering

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Bioengineering

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

2,164 Views

•

10:17 min

•

May 16, 2022

DOI:

10.3791/63622-v

DOI:

10.3791/63622-v

•

10:17 min

May 16, 2022

•

2155 Views

Asli Pinar Zorba Yildiz^1,2,4, Hakan Darici^3,4,5, Burcak Yavuz^2,4,6, Emrah Sefik Abamor², Ceren Ozdemir^2,5, Muge Elif Yasin⁴, Melahat Bagirova^2,7, Adil Allahverdiyev^2,7, Erdal Karaoz^3,4,5,8

¹Vocational School of Health Services,Istinye University ²Chemical Metallurgy Faculty,Yildiz Technical University ³Faculty of Medicine, Department of Histology & Embryology,Istinye University ⁴3D Bioprinting Design & Prototyping R&D Center,Istinye University ⁵Stem Cell, and Tissue Engineering R&D Center,Istinye University ⁶Vocational School of Health Services,Altinbas University ⁷The V. Akhundov National Scientific Research Medical Prophylactic Institute ⁸Center for Stem Cells and Regenerative Medicine (LivMedCell),Liv Hospital

Summary

In this manuscript, we demonstrate the preparation of a biohybrid hydrogel bioink containing graphene for use in peripheral tissue engineering. Using this 3D biohybrid material, the neural differentiation protocol of stem cells is performed. This can be an important step in bringing similar biomaterials to the clinic.