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JoVE Journal Bioengineering
Fremstilling af størrelsesstyrede og emulsionsfrie chitosan-genipinmikrogeler til vævstekniske applikationer
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Fremstilling af størrelsesstyrede og emulsionsfrie chitosan-genipinmikrogeler til vævstekniske applikationer

Article DOI: 10.3791/63857-v • 05:26 min • April 13th, 2022
April 13th, 2022 •
1, 2, 2, 1
1Department of Chemical and Biological Engineering, Colorado School of Mines, 2Department of Orthopedics, University of Colorado Anschutz Medical Campus

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Den foreliggende protokol beskriver en ikke-emulsionsbaseret metode til fremstilling af chitosan-genipin-mikrogeler. Størrelsen af disse mikrogeler kan styres præcist, og de kan vise pH-afhængig hævelse, nedbrydes in vivo og belastes med terapeutiske molekyler, der frigives over tid på en vedvarende måde, hvilket gør dem yderst relevante for vævstekniske applikationer.

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