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Immunology and Infection

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JoVE Journal Immunology and Infection
A Minimally Invasive, Accurate, and Efficient Technique for Intrathymic Injection in Mice
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A Minimally Invasive, Accurate, and Efficient Technique for Intrathymic Injection in Mice

Article DOI: 10.3791/64309-v • 07:17 min • August 23rd, 2022
August 23rd, 2022 •
*1, *2, 2, 2,3,4
1Department of Radiology, Hackensack University Medical Center, 2Center for Discovery and Innovation, Hackensack Meridian Health, 3Department of Pediatrics, Hackensack University Medical Center, 4Department of Oncology, Georgetown University
* These authors contributed equally

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Summary
Automatic Translation

The present protocol describes an interventional radiology procedure established for intrathymic injection in mice to avoid the risk of open surgery and improve the accuracy of blind percutaneous injections.

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Intrathymic Injection Mice Minimally Invasive Technique Accurate Injection Efficient Injection Non-surgical Alternative Blind Injection Methods Atrophy Thymuses Aged Mice Immunodeficient Mice Stress-free Procedure Large-scale Experiments Surgical Stress-related Immunosuppression Interventional Radiologist Depilatory Cream Anesthetic Depth Ophthalmic Ointment Small Animal Ultrasound Imaging Station Heated Platform Medical Adhesive Tape Disinfect Skin
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