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JoVE Journal
Medicine
Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
JoVE Journal
Medicine
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JoVE Journal Medicine
Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Full Text
2,926 Views
08:16 min
September 28, 2022

DOI: 10.3791/64463-v

Milan Kordić1, Josip Dugandžić1, Martina Ratko2, Nikola Habek2,3, Aleksandra Dugandžić2,3

1MKP Ltd., 2Croatian Institute for Brain Research,University of Zagreb, School of Medicine, 3Department of Physiology,University of Zagreb, School of Medicine

Here, we present a protocol for measuring brown adipose tissue activity after a meal in humans and laboratory animals.

Infrared thermography enables the estimation of brown adipose tissue activity in laboratory animals and human participants, regardless of gender, age, or the effects of different pathological conditions. PET-CT fails as a method of choice for measuring brown adipose tissue activity, especially after a meal. Therefore, a noninvasive and more sensitive infrared thermography was developed.

Using infrared thermography, we can determine that the pathophysiological changes in brown adipose tissue activity or bath activity in people with obesity and diabetes mellitus, and determine drug that can rejuvenate bad activity in these patients. This method could be used to determine the physiological effects of hormones or synthesize therapeutic substances on bad activity in humans and laboratory animals. Ask the participants if they are well-rested and fasted overnight.

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