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En silisosemusemodell etablert ved gjentatt innånding av krystallinsk silikastøv
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En silisosemusemodell etablert ved gjentatt innånding av krystallinsk silikastøv

Article DOI: 10.3791/64862-v • 10:45 min • January 6th, 2023
January 6th, 2023 •
*1,2,3,4, *1,2,3,4, 1,3,4, 1,4, 1,4, 1,4, 1,2,3,4, 1,2,3,4
1Key Laboratory of Industrial Dust Control and Occupational Health of the Ministry of Education, Anhui University of Science and Technology, 2Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institutes, Anhui University of Science and Technology, 3Anhui Province Engineering Laboratory of Occupational Health and Safety, 4School of Medicine, Department of Medical Frontier Experimental Center, Anhui University of Science and Technology
* These authors contributed equally

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Denne protokollen beskriver en metode for å etablere en musemodell av silikose gjennom gjentatt eksponering for silikasuspensjoner via et nesedrypp. Denne modellen kan effektivt, praktisk og fleksibelt etterligne den patologiske prosessen med human silikose med høy repeterbarhet og økonomi.

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Medisin utgave 191 musemodell innånding patofysiologi screening behandling kliniske symptomer akutt / kronisk transformasjonsprosess prosedyrer CSD-pulver saltvannssuspensjon ultralyd vannbad anestesi aspirasjon neseborinnånding musebur
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