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Journal / Immunology and Infection / 유전자 변형 Plasmodium berghei Sporozoites…
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Immunology and Infection

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JoVE Journal Immunology and Infection
유전자 변형 Plasmodium berghei Sporozoites 생성
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유전자 변형 Plasmodium berghei Sporozoites 생성

Article DOI: 10.3791/64992-v • 10:16 min • May 5th, 2023
May 5th, 2023 •
1, 1,2
1Center for Tropical and Emerging Global Diseases, University of Georgia, 2Department of Cellular Biology, University of Georgia

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말라리아는 감염된 모기에 의한 Plasmodium의 sporozoite 단계 접종을 통해 전염됩니다. 형질전환 플라스모디움 은 말라리아의 생물학을 더 잘 이해할 수 있게 해주었고 말라리아 백신 개발 노력에 직접적으로 기여했습니다. 여기에서는 형질전환 Plasmodium berghei sporozoites를 생성하는 간소화된 방법론을 설명합니다.

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유전자 변형 Plasmodium Berghei Sporozoites 말라리아 기생충 Plasmodium Anopheles 모기 간 단계 발달 임상 말라리아 면역 반응 유전자 변형 기생충 혈액 단계 P. Berghei 모기 타액선 생체 내 실험 체외 실험 녹색 형광 단백질(GFP) 간 단계 말라리아
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