Hand-Rearing Method for Infant Marmosets

Hao Sun; Rui Li; Yingxu Lin; Xinyuan Cao; Lingzhu Fan; Guanglong Sun; Min Xie; Lin Zhu; Chencen Yu; Ruolan Cai; Chenfei Lyu; Xiaohui Wang; Yuanqing Zhang; Siyi Bai; Runze Qi; Binliang Tang; Guoqiang Jia; Xinjian Li; Lixia Gao

doi:10.3791/65296

Journal

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Biology

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Hand-Rearing Method for Infant Marmosets

JoVE Journal
Biology

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JoVE Journal Biology

Hand-Rearing Method for Infant Marmosets

1,714 Views

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04:52 min

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June 09, 2023

DOI:

10.3791/65296-v

DOI:

10.3791/65296-v

•

04:52 min

June 09, 2023

•

8 Views

Hao Sun^1,2, Rui Li¹, Yingxu Lin^1,2, Xinyuan Cao¹, Lingzhu Fan¹, Guanglong Sun¹, Min Xie¹, Lin Zhu¹, Chencen Yu¹, Ruolan Cai¹, Chenfei Lyu¹, Xiaohui Wang^1,2, Yuanqing Zhang^1,2, Siyi Bai^1,2, Runze Qi¹, Binliang Tang^1,3, Guoqiang Jia^1,4, Xinjian Li^1,2,4, Lixia Gao^1,2,4

¹Department of Neurology of the Second Affiliated Hospital and Interdisciplinary Institute of Neuroscience and Technology, School of Medicine,Zhejiang University, ²Key Laboratory of Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science,Zhejiang University, ³Rehabilitation Medicine Center, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital,Hangzhou Medical College, ⁴NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, School of Brain Science and Brain Medicine,Zhejiang University

Transcript

The marmoset is a highly vocal and highly social New World monkey with high reproductive rate. We are interested in the sound processing in the brain of marmosets, the vocal development and vocal communications of infant marmosets, as well as the establishment of marmoset models of human mental diseases. The current big challenge is the shortage of marmoset supply, which cannot meet the needs of scientific research and thus, impede the progress of marmoset studies.

Another challenge is the lack of experiments in maintaining a marmoset colony. This hand-rearing method significantly increases the survival rate of marmoset infants, and provides the opportunity to study the development of marmoset infants with a similar genetic backgrounds, but raised in different postnatal environments.

Summary

Here, we describe a hand-rearing method for raising infant marmosets in an animal incubator. This method greatly increases the survival rate of marmoset infants, which provides the opportunity to study the development of marmoset infants with similar genetic backgrounds raised in different postnatal environments.