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Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors
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Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE

Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors

DOI:
10.3791/65430-v

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01:41 min

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August 25, 2023

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, , , ,
1Hollings Cancer Center,Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine,Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics,University of Michigan, Ann Arbor

Tags

Keywords: Genetic ProfilingGenome-scale Dropout ScreeningMalignant Peripheral Nerve Sheath TumorsNF1Unbiased ScreeningSingle-cell SequencingBioinformaticsErbB3Lysophosphatidic Acid Receptor 3Schwann CellsNeurofibromatosis Type 1Targeted TherapiesFunctional Genomic Screening

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