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Differentiating Human Pluripotent Stem Cells into Pancreatic β-Cells

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Author Spotlight: Advancements and Challenges in β-Cells Differentiation from Pluripotent Stem Cells

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Biology

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JoVE Journal Biology

Optimized Protocol for Generating Functional Pancreatic Insulin-secreting Cells from Human Pluripotent Stem Cells

Author Spotlight: Advancements and Challenges in β-Cells Differentiation from Pluripotent Stem Cells

Differentiating Human Pluripotent Stem Cells into Pancreatic β-Cells

DOI:

10.3791/65530-v

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01:29 min

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February 02, 2024

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Ines Cherkaoui, Qian Du, Dieter Egli, Shivani Misra³, Guy A. Rutter^4,5

¹Department of Metabolism, Digestion and Reproduction, Faculty of Medicine,Cell Biology and Functional Genomics, ²Departments of Pediatrics, Naomi Berrie Diabetes Center, Obstetrics and Gynecology, Columbia Stem Cell Initiative, Columbia University Irving Medical Center,Columbia University, ³Department of Diabetes,Imperial College Healthcare NHS Trust, ⁴Faculté de Médicine,Université de Montréal, ⁵Lee Kong Chian Imperial Medical School,Nanyang Technological University

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Keywords: Human Pluripotent Stem Cells Beta Cell Differentiation Insulin-producing Cells Pancreatic Endocrine Progenitors Diabetes Research Glucose-stimulated Insulin Secretion

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