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Chapters
- 00:00Title
- 00:11Introduction
- 01:02Performing Aldicarb Exposure Paradigm
- 10:07Performing Pentylenetetrazole (PTZ) Exposure Paradigm
- 16:24Conclusion
This video demonstrates how to employ two neural stimulants, aldicarb and pentylenetetrazole (PTZ), in complementary ways to study synaptic function in the nematode, C. elegans. This complementary approach may also be used to shed light on evolutionarily conserved mechanisms for modulating neuronal synchrony and has implications for epilepsy and seizures.
Tags
Pharmacological CharacterizationC. ElegansSynaptic Transmission MutantsNeurotransmissionNeural StimulantsAcetylcholinesterase InhibitorAldicarbGamma-aminobutyric Acid Receptor AntagonistPentylenetetrazoleC. Elegans Neuromuscular JunctionsGABAergic Motor NeuronsRMEsAcetylcholineAntagonistic Neural CircuitsBody Wall MusclesLocomotionLaser AblationAldicarb Exposure
