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Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants
 

Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants

Article DOI: 10.3791/837
August 18th, 2008

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Summary August 18th, 2008

This video demonstrates how to employ two neural stimulants, aldicarb and pentylenetetrazole (PTZ), in complementary ways to study synaptic function in the nematode, C. elegans. This complementary approach may also be used to shed light on evolutionarily conserved mechanisms for modulating neuronal synchrony and has implications for epilepsy and seizures.

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