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JoVE Journal Bioengineering
One Minute, Sub-One-Watt Fotothermische Tumor Ablation behulp Porphysomes, Intrinsieke Multifunctionele nanovesicles
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One Minute, Sub-One-Watt Fotothermische Tumor Ablation behulp Porphysomes, Intrinsieke Multifunctionele nanovesicles

Article DOI: 10.3791/50536-v • 09:51 min • September 17th, 2013
September 17th, 2013 •
1,2,3, 4, 1,2,3
1Department of Pharmaceutical Sciences, University of Toronto, 2The Institute of Biomaterials and Biomedical Engineering, University of Toronto, 3Ontario Cancer Institute, Campbell Family Institute For Cancer Research and Techna Institute, 4Department of Biomedical Engineering, University at Buffalo, The State University of New York

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We ontwikkelden nieuwe intrinsieke multifunctionele nanovesicles genaamd porphysomes, welke structuur-afhankelijke fluorescentie zelf-afschrikken en unieke fotothermische eigenschappen hebben, waardoor het als krachtige fotothermisch therapie agenten. We formuleerden porphysomes behulp van hoge druk extrusie en onderzocht hun fotothermische therapie werkzaamheid bij een xenograft tumor model.

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Biotechniek Nanodeeltjes Porphysome fotothermische therapie nanodeeltje porfyrine
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