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Journal / Bioengineering / Ingeniería tisular tridimensional alineado…
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Bioengineering

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JoVE Journal Bioengineering
Ingeniería tisular tridimensional alineado astrositos redes para recapitular los mecanismos del desarrollo y facilitar la regeneración del sistema nervioso
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Ingeniería tisular tridimensional alineado astrositos redes para recapitular los mecanismos del desarrollo y facilitar la regeneración del sistema nervioso

Article DOI: 10.3791/55848-v • 08:56 min • January 10th, 2018
January 10th, 2018 •
*1,2,3, *1,2,4, 1,2,4, 1,2, 1,5, 1,5, 1,2,4, 1,2,5
1Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2Center for Neurotrauma, Neurodegeneration & Restoration, Michael J. Crescenz Veterans Affairs Medical Center, 3School of Biomedical Engineering, Drexel University, 4Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 5Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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Nos muestra el desarrollo de los paquetes uno mismo-montado, tridimensionales de somata astrocytic longitudinalmente alineado y procesos dentro de un protector nuevo biomaterial. Estos diseñados "andamios de vida", que diámetro de la escala del micrón pero extiende centímetros de longitud, puede servir como bancos de pruebas para estudiar los mecanismos del desarrollo neurológico o facilitar la Neurorregeneración por dirige la migración neuronal y axonal pathfinding.

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Bioingeniería número 131 tejido Neural ingeniería vida andamios neurotrauma Neurorregeneración migración celular pathfinding axon redes de astrositos células madre neurales
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