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JoVE Journal Neuroscience
Eksperimentelle modeller for å studere nevrobeskyttelsen av sur postkonditionering mot cerebral iskemi
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Eksperimentelle modeller for å studere nevrobeskyttelsen av sur postkonditionering mot cerebral iskemi

Article DOI: 10.3791/55931-v • 10:13 min • July 31st, 2017
July 31st, 2017 •
*1, *1, 1, 1, 1, 1, 1
1Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Department of Pharmacology, Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University
* These authors contributed equally

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Syrenettkondisjonering beskytter mot cerebral iskemi. Her presenterer vi to modeller for å utføre APC. De er oppnådd henholdsvis ved overføring corticostriatal skiver til sur buffer etter oksygen-glukosemangel in vitro, og ved inhalering 20% CO2 etter tilstopping av midtre cerebralarterie in vivo.

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Neurobiologi utgave 125 cerebral iskemi sur postkondisjonering kortikostriatal skive oksygen-glukose deprivasjon midtre cerebral arterie okklusjon (MCAO) hjerneinfarkt volum tidsvindu
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