Benedict R. Lucchesi Department of Pharmacology University of Michigan Biography Publications Institution JoVE Articles Benedict R. Lucchesi has not added a biography. If you are Benedict R. Lucchesi and would like to personalize this page please email our Author Liaison for assistance. Publications Are ECG Premature Complexes Induced by Ultrasonic Cavitation Electrophysiological Responses to Irreversible Cardiomyocyte Injury? Ultrasound in Medicine & Biology. Feb, 2011 | Pubmed ID: 21257092 Thrombogenesis with Continuous Blood Flow in the Inferior Vena Cava. A Novel Mouse Model Thrombosis and Haemostasis. Aug, 2010 | Pubmed ID: 20589322 Coxibs Interfere with the Action of Aspirin by Binding Tightly to One Monomer of Cyclooxygenase-1 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19955429 Cardiac Arrhythmia and Injury Induced in Rats by Burst and Pulsed Mode Ultrasound with a Gas Body Contrast Agent Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Nov, 2009 | Pubmed ID: 19854967 Estrogen Protects the Heart from Ischemia-reperfusion Injury Via COX-2-derived PGI2 Journal of Cardiovascular Pharmacology. Sep, 2008 | Pubmed ID: 18806603 Estrogen-mediated Protection in Myocardial Ischemia-reperfusion Injury Cardiovascular Toxicology. 2008 | Pubmed ID: 18683081 Disodium Disuccinate Astaxanthin Prevents Carotid Artery Rethrombosis and Ex Vivo Platelet Activation Pharmacology. 2008 | Pubmed ID: 18477858 Apolipoprotein A-IMilano/POPC Complex Attenuates Post-ischemic Ventricular Dysfunction in the Isolated Rabbit Heart Atherosclerosis. Apr, 2008 | Pubmed ID: 17945238 Effects of Cyclooxygenase Inhibition on Canine Coronary Artery Blood Flow and Thrombosis American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2008 | Pubmed ID: 17921331 The Pathway-selective Estrogen Receptor Ligand WAY-169916 Reduces Infarct Size After Myocardial Ischemia and Reperfusion by an Estrogen Receptor Dependent Mechanism Journal of Cardiovascular Pharmacology. Jun, 2007 | Pubmed ID: 17577105 Medroxyprogesterone Acetate Prevents the Cardioprotective and Anti-inflammatory Effects of 17beta-estradiol in an in Vivo Model of Myocardial Ischemia and Reperfusion American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2007 | Pubmed ID: 17434982 Sulodexide: a Renewed Interest in This Glycosaminoglycan Cardiovascular Drug Reviews. Fall-Winter, 2006 | Pubmed ID: 17214598 Preclinical Evaluation of S18886 in an Experimental Model of Coronary Arterial Thrombosis Journal of Cardiovascular Pharmacology. Nov, 2006 | Pubmed ID: 17110806 Effect of Sodium/hydrogen Exchange Inhibition on Myocardial Infarct Size After Coronary Artery Thrombosis and Thrombolysis Pharmacology. 2006 | Pubmed ID: 16899991 Microvascular Permeabilization and Cardiomyocyte Injury Provoked by Myocardial Contrast Echocardiography in a Canine Model Journal of the American College of Cardiology. Apr, 2006 | Pubmed ID: 16580537 Effect of Thrombolysis on Myocardial Injury: Recombinant Tissue Plasminogen Activator Vs. Alfimeprase American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2006 | Pubmed ID: 16243915 Intimatan (dermatan 4,6-O-disulfate) Prevents Rethrombosis After Successful Thrombolysis in the Canine Model of Deep Vessel Wall Injury Thrombosis Research. 2006 | Pubmed ID: 15893368 The Antithrombotic Effect of Melagatran in Combination with Clopidogrel And/or Aspirin (carotid Artery Primary Thrombosis Study) Journal of Cardiovascular Pharmacology. Oct, 2005 | Pubmed ID: 16160608 Activation of Estrogen Receptor-alpha Protects the in Vivo Rabbit Heart from Ischemia-reperfusion Injury American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2005 | Pubmed ID: 15994857 Disodium Disuccinate Astaxanthin (Cardax) Attenuates Complement Activation and Reduces Myocardial Injury Following Ischemia/reperfusion The Journal of Pharmacology and Experimental Therapeutics. Aug, 2005 | Pubmed ID: 15872041 Ischemia Depletes Dystrophin and Inhibits Protein Synthesis in the Canine Heart: Mechanisms of Myocardial Ischemic Injury Journal of Molecular and Cellular Cardiology. May, 2005 | Pubmed ID: 15850566 International Immunopharmacology. Feb, 2005 | Pubmed ID: 15652767 Sulodexide Attenuates Myocardial Ischemia/reperfusion Injury and the Deposition of C-reactive Protein in Areas of Infarction Without Affecting Hemostasis The Journal of Pharmacology and Experimental Therapeutics. Feb, 2005 | Pubmed ID: 15365091 Apolipoprotein A-IMilano and 1-palmitoyl-2-oleoyl Phosphatidylcholine Complex (ETC-216) Protects the in Vivo Rabbit Heart from Regional Ischemia-reperfusion Injury The Journal of Pharmacology and Experimental Therapeutics. Dec, 2004 | Pubmed ID: 15375174 The Preparation and Characterization of Novel Peptide Antagonists to Thrombin and Factor VIIa and Activation of Protease-activated Receptor 1 The Journal of Pharmacology and Experimental Therapeutics. Nov, 2004 | Pubmed ID: 15210836 Risk of Ventricular Proarrhythmia with Selective Opening of the Myocardial Sarcolemmal Versus Mitochondrial ATP-gated Potassium Channel The Journal of Pharmacology and Experimental Therapeutics. May, 2004 | Pubmed ID: 14747611 17Beta-estradiol As a Receptor-mediated Cardioprotective Agent The Journal of Pharmacology and Experimental Therapeutics. Oct, 2003 | Pubmed ID: 12893838 Prevention of Carotid Artery Thrombosis After Oral Administration of the Glycoprotein IIb/IIIa Antagonist CRL42796 Journal of Cardiovascular Pharmacology. Jul, 2003 | Pubmed ID: 12827029 Glycoprotein IIb/IIIa Receptor Antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-[[2-([4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] Butanoyl]amino)acetyl]amino]propanoic Acid Dihydrochloride (CRL42796), in Combination with Aspirin And/or Enoxaparin, Prevents Coronary Artery Rethrombosis After Successful Thrombolytic Treatment by Recombinant Tissue Plasminogen Activator The Journal of Pharmacology and Experimental Therapeutics. Aug, 2003 | Pubmed ID: 12734394 SNC-80-induced Preconditioning: Selective Activation of the Mitochondrial Adenosine Triphosphate-gated Potassium Channel Journal of Cardiovascular Pharmacology. May, 2003 | Pubmed ID: 12717105 Apoptosis in Myocardial Infarction Annals of Medicine. 2002 | Pubmed ID: 12523502 C-reactive-protein-associated Increase in Myocardial Infarct Size After Ischemia/reperfusion The Journal of Pharmacology and Experimental Therapeutics. Dec, 2002 | Pubmed ID: 12438521 Prevention of Experimental Carotid and Coronary Artery Thrombosis by the Glycoprotein IIb/IIIa Receptor Antagonist CRL42796 British Journal of Pharmacology. Jul, 2002 | Pubmed ID: 12110617 Intimatan Prevents Arterial and Venous Thrombosis in a Canine Model of Deep Vessel Wall Injury The Journal of Pharmacology and Experimental Therapeutics. Jun, 2002 | Pubmed ID: 12023550 Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis Jose A. Diaz1, Shirley K. Wrobleski1, Angela E. Hawley1, Benedict R. Lucchesi2, Thomas W. Wakefield1, Daniel D. Myers, Jr.1 1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan, 2Department of Pharmacology, University of Michigan JoVE 2737 Medicine
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis Jose A. Diaz1, Shirley K. Wrobleski1, Angela E. Hawley1, Benedict R. Lucchesi2, Thomas W. Wakefield1, Daniel D. Myers, Jr.1 1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan, 2Department of Pharmacology, University of Michigan JoVE 2737 Medicine