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Articles by Chia-Yen Wu in JoVE

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Efficient Differentiation of Mouse Embryonic Stem Cells into Motor Neurons


JoVE 3813 6/09/2012

Nemours Biomedical Research, Alfred I. duPont Hospital for Children

We developed a new protocol to improve efficiency of in vitro differentiation of mouse embryonic stem cells into motor neurons. The differentiated ES cells acquired motor neurons features as evidenced by expression of neuronal and motor neuron markers using immunohistochemical techniques.

Other articles by Chia-Yen Wu on PubMed

PI3Ks Maintain the Structural Integrity of T-tubules in Cardiac Myocytes

Phosphoinositide 3-kinases (PI3Ks) regulate numerous physiological processes including some aspects of cardiac function. Although regulation of cardiac contraction by individual PI3K isoforms has been studied, little is known about the cardiac consequences of downregulating multiple PI3Ks concurrently.

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