Heather Whetstone Sickkids Research Institute The Hospital for Sick Children Biography Publications Institution JoVE Articles Heather Whetstone has not added a biography. If you are Heather Whetstone and would like to personalize this page please email our Author Liaison for assistance. Publications Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Pharmacology. 2023 | Pubmed ID: 36696888 Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis Frontiers in Immunology. 2021 | Pubmed ID: 33732230 PRMT5 Inhibition Disrupts Splicing and Stemness in Glioblastoma Nature Communications. 02, 2021 | Pubmed ID: 33579912 Single-cell Chromatin Accessibility Profiling of Glioblastoma Identifies an Invasive Cancer Stem Cell Population Associated with Lower Survival ELife. Jan, 2021 | Pubmed ID: 33427645 Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2 Granule Neuron Precursor Cell Reports. Apr, 2020 | Pubmed ID: 32294450 Aged Hind-limb Clasping Experimental Autoimmune Encephalomyelitis Models Aspects of the Neurodegenerative Process Seen in Multiple Sclerosis Proceedings of the National Academy of Sciences of the United States of America. Nov, 2019 | Pubmed ID: 31641069 A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression Neuron. Nov, 2018 | Pubmed ID: 30344046 Fate Mapping of Human Glioblastoma Reveals an Invariant Stem Cell Hierarchy Nature. Sep, 2017 | Pubmed ID: 28854171 ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells Cell Stem Cell. Aug, 2017 | Pubmed ID: 28712938 Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype Cell Reports. Jul, 2016 | Pubmed ID: 27425618 Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells Cancer Cell. Jun, 2016 | Pubmed ID: 27300435 Hedgehog Inhibits β-catenin Activity in Synovial Joint Development and Osteoarthritis The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27018594 Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia American Journal of Human Genetics. Dec, 2015 | Pubmed ID: 26637977 β-Catenin-regulated Myeloid Cell Adhesion and Migration Determine Wound Healing The Journal of Clinical Investigation. Jun, 2014 | Pubmed ID: 24837430 T-lymphocytes Enable Osteoblast Maturation Via IL-17F During the Early Phase of Fracture Repair PloS One. 2012 | Pubmed ID: 22768215 Beta-catenin Signaling Plays a Disparate Role in Different Phases of Fracture Repair: Implications for Therapy to Improve Bone Healing PLoS Medicine. Jul, 2007 | Pubmed ID: 17676991 PTHrP Regulates Growth Plate Chondrocyte Differentiation and Proliferation in a Gli3 Dependent Manner Utilizing Hedgehog Ligand Dependent and Independent Mechanisms Developmental Biology. May, 2007 | Pubmed ID: 17328886 Beta-catenin Regulates Wound Size and Mediates the Effect of TGF-beta in Cutaneous Healing FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2006 | Pubmed ID: 16581977 Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis (Video) | JoVE Carmen C. Ucciferri1, Annette Gower2, Nuria Alvarez-Sanchez1,2, Heather Whetstone3, Valeria Ramaglia1, Jennifer L. Gommerman1, Koroboshka Brand-Arzamendi2, Raphael Schneider2,4, Shannon E Dunn1,2,5 1Department of Immunology, University of Toronto, 2Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, 3Sickkids Research Institute, The Hospital for Sick Children, 4BARLO MS Centre, St. Michael’s Hospital, 5Women’s College Research Institute, Women’s College Hospital JoVE 65738 Immunology and Infection
Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis (Video) | JoVE Carmen C. Ucciferri1, Annette Gower2, Nuria Alvarez-Sanchez1,2, Heather Whetstone3, Valeria Ramaglia1, Jennifer L. Gommerman1, Koroboshka Brand-Arzamendi2, Raphael Schneider2,4, Shannon E Dunn1,2,5 1Department of Immunology, University of Toronto, 2Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, 3Sickkids Research Institute, The Hospital for Sick Children, 4BARLO MS Centre, St. Michael’s Hospital, 5Women’s College Research Institute, Women’s College Hospital JoVE 65738 Immunology and Infection
