Howard D. White Department of Physiological Sciences Eastern Virginia Medical School Biography Publications Institution JoVE Articles Howard D. White has not added a biography. If you are Howard D. White and would like to personalize this page please email our Author Liaison for assistance. Publications On-grid and In-flow Mixing for Time-resolved Cryo-EM Acta Crystallographica. Section D, Structural Biology. Oct, 2021 | Pubmed ID: 34605427 Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin Journal of Molecular Biology. 09, 2021 | Pubmed ID: 34329643 The Structure of the Native Cardiac Thin Filament at Systolic Ca Levels Proceedings of the National Academy of Sciences of the United States of America. 03, 2021 | Pubmed ID: 33753506 High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex Structure (London, England : 1993). 01, 2021 | Pubmed ID: 33065066 Need for Speed: Examining Protein Behavior During CryoEM Grid Preparation at Different Timescales Structure (London, England : 1993). 11, 2020 | Pubmed ID: 32814033 Sample Deposition Onto Cryo-EM Grids: from Sprays to Jets and Back Acta Crystallographica. Section D, Structural Biology. Apr, 2020 | Pubmed ID: 32254058 A Cryo-EM Grid Preparation Device for Time-resolved Structural Studies IUCrJ. Nov, 2019 | Pubmed ID: 31709058 Investigation into the Mechanism of Thin Filament Regulation by Transient Kinetics and Equilibrium Binding: Is There a Conflict? The Journal of General Physiology. 05, 2019 | Pubmed ID: 30824574 N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament Structure (London, England : 1993). 12, 2018 | Pubmed ID: 30270174 Distinct Sites in Tropomyosin Specify Shared and Isoform-specific Regulation of Myosins II and V Cytoskeleton (Hoboken, N.J.). 04, 2018 | Pubmed ID: 29500902 The Shaker-1 Mouse Myosin VIIa Deafness Mutation Results in a Severely Reduced Rate of the ATP Hydrolysis Step The Journal of Biological Chemistry. 01, 2018 | Pubmed ID: 29167268 Ca-induced Movement of Tropomyosin on Native Cardiac Thin Filaments Revealed by Cryoelectron Microscopy Proceedings of the National Academy of Sciences of the United States of America. 06, 2017 | Pubmed ID: 28607071 C0 and C1 N-terminal Ig Domains of Myosin Binding Protein C Exert Different Effects on Thin Filament Activation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26831109 Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine β-cardiac Myosin Biochemistry. Mar, 2015 | Pubmed ID: 25680381 Modulation of Thin Filament Activation of Myosin ATP Hydrolysis by N-terminal Domains of Cardiac Myosin Binding Protein-C Biochemistry. Oct, 2014 | Pubmed ID: 25265574 Coupling of Two Non-processive Myosin 5c Dimers Enables Processive Stepping Along Actin Filaments Scientific Reports. May, 2014 | Pubmed ID: 24809456 Regulation of Actin-myosin Interaction by Conserved Periodic Sites of Tropomyosin Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23091026 Mechanism of Regulation of Native Cardiac Muscle Thin Filaments by Rigor Cardiac Myosin-S1 and Calcium The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20696756 The SAH Domain Extends the Functional Length of the Myosin Lever Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 20018767 Switch 1 Mutation S217A Converts Myosin V into a Low Duty Ratio Motor The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19008235 Direct Observation of the Mechanochemical Coupling in Myosin Va During Processive Movement Nature. Sep, 2008 | Pubmed ID: 18668042 Smooth Muscle Myosin Phosphorylated at Single Head Shows Sustained Mechanical Activity The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18408003 Kinetics of ADP Dissociation from the Trail and Lead Heads of Actomyosin V Following the Power Stroke The Journal of Biological Chemistry. Jan, 2008 | Pubmed ID: 17965414 Real-time Measurement of Myosin-nucleotide Noncovalent Complexes by Electrospray Ionization Mass Spectrometry Biophysical Journal. Aug, 2007 | Pubmed ID: 17483158 Kinetic Mechanism of MyosinV-S1 Using a New Fluorescent ATP Analogue Biochemistry. Oct, 2006 | Pubmed ID: 17059220 The Prepower Stroke Conformation of Myosin V The Journal of Cell Biology. Dec, 2002 | Pubmed ID: 12499355 Mechanism of Regulation of Phosphate Dissociation from Actomyosin-ADP-Pi by Thin Filament Proteins Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12486217 Observation of Transient Disorder During Myosin Subfragment-1 Binding to Actin by Stopped-flow Fluorescence and Millisecond Time Resolution Electron Cryomicroscopy: Evidence That the Start of the Crossbridge Power Stroke in Muscle Has Variable Geometry Proceedings of the National Academy of Sciences of the United States of America. Jan, 1999 | Pubmed ID: 9892656 Preparazione rapida della griglia per la microscopia crioeletletnica risolta nel tempo David P. Klebl1, Frank Sobott2, Howard D. White3, Stephen P. Muench1 1School of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 2School of Molecular and Cellular Biology, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 3Department of Physiological Sciences, Eastern Virginia Medical School JoVE 62199 Biochemistry
Preparazione rapida della griglia per la microscopia crioeletletnica risolta nel tempo David P. Klebl1, Frank Sobott2, Howard D. White3, Stephen P. Muench1 1School of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 2School of Molecular and Cellular Biology, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, 3Department of Physiological Sciences, Eastern Virginia Medical School JoVE 62199 Biochemistry
