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Articles by Jonathan Collins in JoVE
JoVE Clinical and Translational Medicine
增强细胞凋亡和自噬的诱导合成一种新型的C-1 7-deoxypancratistatin的类似物在人类乳癌细胞和神经母细胞瘤与他莫昔芬
1Department of Chemistry and Biochemistry, University of Windsor, 2Chemistry Department and Centre for Biotechnology, Brock University
我们已合成了新型防癌抗癌作为本地pancratistatin活动相媲美的pancratistatin模拟;有趣的是，与他莫昔芬治疗组合的产生在细胞凋亡和自噬的诱导线粒体与非癌成纤维细胞的影响最小的目标大幅提高。因此，与他莫昔芬结合JCTH-4可以提供一个安全的抗癌疗法。
