Lianfu Deng Department of Orthopedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital Shanghai Jiao Tong University School of Medicine Biography Publications Institution JoVE Articles Lianfu Deng has not added a biography. If you are Lianfu Deng and would like to personalize this page please email our Author Liaison for assistance. Publications Black Phosphorus Accelerates Bone Regeneration Based on Immunoregulation Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Nov, 2023 | Pubmed ID: 37953457 Geometric Angles and Gene Expression in Cells for Structural Bone Regeneration Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Sep, 2023 | Pubmed ID: 37775309 Hydrogen Ion Capturing Hydrogel Microspheres for Reversing Inflammaging Advanced Materials (Deerfield Beach, Fla.). Sep, 2023 | Pubmed ID: 37699155 A General Method for Endowing Hydrophobic Nanoparticles with Water Dispersion Abilities Journal of Materials Chemistry. B. Sep, 2023 | Pubmed ID: 37584086 Click Chemistry Extracellular Vesicle/peptide/chemokine Nanocarriers for Treating Central Nervous System Injuries Acta Pharmaceutica Sinica. B. May, 2023 | Pubmed ID: 37250158 In Situ Sustained Macrophage-Targeted Nanomicelle-Hydrogel Microspheres for Inhibiting Osteoarthritis Research (Washington, D.C.). 2023 | Pubmed ID: 37223475 Circadian Clock Regulation Via Biomaterials for Nucleus Pulposus Advanced Materials (Deerfield Beach, Fla.). Aug, 2023 | Pubmed ID: 37060338 3D Biomimetic Calcified Cartilaginous Callus That Induces Type H Vessels Formation and Osteoclastogenesis Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jun, 2023 | Pubmed ID: 36999832 Visualizable and Lubricating Hydrogel Microspheres Via NanoPOSS for Cartilage Regeneration Advanced Science (Weinheim, Baden-Wurttemberg, Germany). May, 2023 | Pubmed ID: 36973540 Engineered Extracellular Vesicles for Ischemic Stroke Treatment Innovation (Cambridge (Mass.)). Mar, 2023 | Pubmed ID: 36923027 Interfering Biosynthesis by Nanoscale Metal-organic Frameworks for Enhanced Radiation Therapy Biomaterials. Apr, 2023 | Pubmed ID: 36764193 Motion Lubrication Suppressed Mechanical Activation Via Hydrated Fibrous Gene Patch for Tendon Healing Science Advances. Feb, 2023 | Pubmed ID: 36763658 Vascularized Polypeptide Hydrogel Modulates Macrophage Polarization for Wound Healing Acta Biomaterialia. Jan, 2023 | Pubmed ID: 36396041 Regulated Macrophage Immune Microenvironment in 3D Printed Scaffolds for Bone Tumor Postoperative Treatment Bioactive Materials. Jan, 2023 | Pubmed ID: 35574049 Desferrioxamine Alleviates UHMWPE Particle-induced Osteoclastic Osteolysis by Inhibiting Caspase-1-dependent Pyroptosis in Osteocytes Journal of Biological Engineering. Dec, 2022 | Pubmed ID: 36482442 MScanFit Motor Unit Number Estimation of Abductor Pollicis Brevis: Findings from Different Experimental Parameters Frontiers in Aging Neuroscience. 2022 | Pubmed ID: 36325193 Construction of Biomimetic Tissues with Anisotropic Structures Via Stepwise Algorithm-Assisted Bioprinting Small (Weinheim an Der Bergstrasse, Germany). Nov, 2022 | Pubmed ID: 36192165 Construction of Active Protein Materials: Manipulation on Morphology of Salmon Calcitonin Assemblies with Enhanced Bone Regeneration Effect Advanced Materials (Deerfield Beach, Fla.). Nov, 2022 | Pubmed ID: 36103707 Inflammation Self-Limiting Electrospun Fibrous Tape Via Regional Immunity for Deep Soft Tissue Repair Small (Weinheim an Der Bergstrasse, Germany). Sep, 2022 | Pubmed ID: 36031400 Development of an Orally Active Small-Molecule Inhibitor of Receptor Activator of Nuclear Factor-κB Ligand Journal of Medicinal Chemistry. Aug, 2022 | Pubmed ID: 35960655 Infiltration from Suspension Systems Enables Effective Modulation of 3D Scaffold Properties in Suspension Bioprinting ACS Applied Materials & Interfaces. Jun, 2022 | Pubmed ID: 35674114 Transporting Hydrogel Via Chinese Acupuncture Needles for Lesion Positioning Therapy Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jun, 2022 | Pubmed ID: 35404511 α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis Frontiers in Pharmacology. 2022 | Pubmed ID: 35370648 Bipolar Metal Flexible Electrospun Fibrous Membrane Based on Metal-Organic Framework for Gradient Healing of Tendon-to-Bone Interface Regeneration Advanced Healthcare Materials. Jun, 2022 | Pubmed ID: 35286782 Motor Unit Number Estimation of the Second Lumbrical Muscle in Human Hand Frontiers in Physiology. 2022 | Pubmed ID: 35283764 A Biomaterial-Based Hedging Immune Strategy for Scarless Tendon Healing Advanced Materials (Deerfield Beach, Fla.). May, 2022 | Pubmed ID: 35267215 Open-Shell Nanosensitizers for Glutathione Responsive Cancer Sonodynamic Therapy Advanced Materials (Deerfield Beach, Fla.). Apr, 2022 | Pubmed ID: 35179801 The Osteoprotective Role of USP26 in Coordinating Bone Formation and Resorption Cell Death and Differentiation. Jun, 2022 | Pubmed ID: 35091692 Transcriptome Analysis Revealed the Symbiosis Niche of 3D Scaffolds to Accelerate Bone Defect Healing Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Mar, 2022 | Pubmed ID: 35040587 Engineering Immunomodulatory and Osteoinductive Implant Surfaces Via Mussel Adhesion-mediated Ion Coordination and Molecular Clicking Nature Communications. Jan, 2022 | Pubmed ID: 35013289 Silencing Gene-Engineered Injectable Hydrogel Microsphere for Regulation of Extracellular Matrix Metabolism Balance Small Methods. Apr, 2022 | Pubmed ID: 34994105 Endogenous Electric-Field-Coupled Electrospun Short Fiber Via Collecting Wound Exudation Advanced Materials (Deerfield Beach, Fla.). Mar, 2022 | Pubmed ID: 34902192 Self-Healing Hydrogel Embodied with Macrophage-Regulation and Responsive-Gene-Silencing Properties for Synergistic Prevention of Peritendinous Adhesion Advanced Materials (Deerfield Beach, Fla.). Feb, 2022 | Pubmed ID: 34816470 Engineered Customizable Microvessels for Progressive Vascularization in Large Regenerative Implants Advanced Healthcare Materials. Feb, 2022 | Pubmed ID: 34797037 Author Correction: MTORC1 Maintains the Tumorigenicity of SSEA-4 High-Grade Osteosarcoma Scientific Reports. Oct, 2021 | Pubmed ID: 34707225 Biological Homeostasis-inspired Light-excited Multistage Nanocarriers Induce Dual Apoptosis in Tumors Biomaterials. Dec, 2021 | Pubmed ID: 34700222 Electrospun Fibers Improving Cellular Respiration Via Mitochondrial Protection Small (Weinheim an Der Bergstrasse, Germany). Nov, 2021 | Pubmed ID: 34636157 Capturing Magnesium Ions Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration ACS Nano. Aug, 2021 | Pubmed ID: 34342981 Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Sep, 2021 | Pubmed ID: 34292669 Gradient Bimetallic Ion-based Hydrogels for Tissue Microstructure Reconstruction of Tendon-to-bone Insertion Science Advances. Jun, 2021 | Pubmed ID: 34162547 CMAP Scan Examination of the First Dorsal Interosseous Muscle After Spinal Cord Injury IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society. 2021 | Pubmed ID: 34106858 Fullerol-hydrogel Microfluidic Spheres for Redox Regulation of Stem Cell Fate and Refractory Bone Healing Bioactive Materials. Dec, 2021 | Pubmed ID: 34095630 Multistage Signal-interactive Nanoparticles Improve Tumor Targeting Through Efficient Nanoparticle-cell Communications Cell Reports. May, 2021 | Pubmed ID: 34038723 Capturing Dynamic Biological Signals Bio-mimicking Hydrogel for Precise Remodeling of Soft Tissue Bioactive Materials. Dec, 2021 | Pubmed ID: 34027237 Pharmaceutical Electrospinning and 3D Printing Scaffold Design for Bone Regeneration Advanced Drug Delivery Reviews. Jul, 2021 | Pubmed ID: 33991588 DNA-Grafted Hyaluronic Acid System with Enhanced Injectability and Biostability for Photo-Controlled Osteoarthritis Gene Therapy Advanced Science (Weinheim, Baden-Wurttemberg, Germany). May, 2021 | Pubmed ID: 33977074 Author Correction: Microenvironment-responsive Immunoregulatory Electrospun Fibers for Promoting Nerve Function Recovery Nature Communications. May, 2021 | Pubmed ID: 33976189 Baicalein Alleviates Osteoarthritis by Protecting Subchondral Bone, Inhibiting Angiogenesis and Synovial Proliferation Journal of Cellular and Molecular Medicine. Jun, 2021 | Pubmed ID: 33939310 Biomimetic Injectable Hydrogel Microspheres with Enhanced Lubrication and Controllable Drug Release for the Treatment of Osteoarthritis Bioactive Materials. Oct, 2021 | Pubmed ID: 33869900 Modulation of Local Overactive Inflammation Via Injectable Hydrogel Microspheres Nano Letters. Mar, 2021 | Pubmed ID: 33543616 Lotus Seedpod-inspired Internal Vascularized 3D Printed Scaffold for Bone Tissue Repair Bioactive Materials. Jun, 2021 | Pubmed ID: 33313444 CircHmbox1 Targeting MiRNA-1247-5p Is Involved in the Regulation of Bone Metabolism by TNF-α in Postmenopausal Osteoporosis Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33425899 Bioinspired Functional Black Phosphorus Electrospun Fibers Achieving Recruitment and Biomineralization for Staged Bone Regeneration Small (Weinheim an Der Bergstrasse, Germany). Dec, 2020 | Pubmed ID: 33230977 High Mineralization Capacity of IDG-SW3 Cells in 3D Collagen Hydrogel for Bone Healing in Estrogen-Deficient Mice Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32984264 Ball-Bearing-Inspired Polyampholyte-Modified Microspheres As Bio-Lubricants Attenuate Osteoarthritis Small (Weinheim an Der Bergstrasse, Germany). Nov, 2020 | Pubmed ID: 32940012 Microenvironment-responsive Immunoregulatory Electrospun Fibers for Promoting Nerve Function Recovery Nature Communications. Sep, 2020 | Pubmed ID: 32908131 Ice-Inspired Superlubricated Electrospun Nanofibrous Membrane for Preventing Tissue Adhesion Nano Letters. Sep, 2020 | Pubmed ID: 32813534 Black Phosphorus-based 2D Materials for Bone Therapy Bioactive Materials. Dec, 2020 | Pubmed ID: 32695934 Thermo-Sensitive Dual-Functional Nanospheres with Enhanced Lubrication and Drug Delivery for the Treatment of Osteoarthritis Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2020 | Pubmed ID: 32428289 A Biomimetic 3D-Self-Forming Approach for Microvascular Scaffolds Advanced Science (Weinheim, Baden-Wurttemberg, Germany). May, 2020 | Pubmed ID: 32382485 Hydration-Enhanced Lubricating Electrospun Nanofibrous Membranes Prevent Tissue Adhesion Research (Washington, D.C.). 2020 | Pubmed ID: 32270140 Cartilage Matrix-inspired Biomimetic Superlubricated Nanospheres for Treatment of Osteoarthritis Biomaterials. Feb, 2020 | Pubmed ID: 32145507 SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes Cell Reports. Feb, 2020 | Pubmed ID: 32049023 Gene-Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jan, 2020 | Pubmed ID: 31921568 Advanced Liposome-loaded Scaffolds for Therapeutic and Tissue Engineering Applications Biomaterials. Feb, 2020 | Pubmed ID: 31918220 Hierarchical Micro/nanofibrous Membranes of Sustained Releasing VEGF for Periosteal Regeneration Biomaterials. Jan, 2020 | Pubmed ID: 31655445 Development of Functional Hydrogels for Heart Failure Journal of Materials Chemistry. B. Mar, 2019 | Pubmed ID: 32254902 Nanoparticle-Embedded Electrospun Fiber-Covered Stent to Assist Intraluminal Photodynamic Treatment of Oesophageal Cancer Small (Weinheim an Der Bergstrasse, Germany). Dec, 2019 | Pubmed ID: 31659867 Recent Advance of Erythrocyte-mimicking Nanovehicles: From Bench to Bedside Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2019 | Pubmed ID: 31644936 Bioinspired Hyaluronic Acid/Phosphorylcholine Polymer with Enhanced Lubrication and Anti-Inflammation Biomacromolecules. Nov, 2019 | Pubmed ID: 31609601 An Electrospun Fiber-covered Stent with Programmable Dual Drug Release for Endothelialization Acceleration and Lumen Stenosis Prevention Acta Biomaterialia. Aug, 2019 | Pubmed ID: 31195144 Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Feb, 2019 | Pubmed ID: 30775235 Self-Nanoemulsifying Electrospun Fiber Enhancing Drug Permeation ACS Applied Materials & Interfaces. Feb, 2019 | Pubmed ID: 30773876 Gene Silencing Via PDA/ERK2-siRNA-Mediated Electrospun Fibers for Peritendinous Antiadhesion Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jan, 2019 | Pubmed ID: 30693181 Differential Expression Profiles and Functional Predication of Circular Ribonucleic Acid in Traumatic Spinal Cord Injury of Rats Journal of Neurotrauma. Aug, 2019 | Pubmed ID: 30681027 TRAF6 Neddylation Drives Inflammatory Arthritis by Increasing NF-κB Activation Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2019 | Pubmed ID: 30626891 Endovascular Metal Devices for the Treatment of Cerebrovascular Diseases Advanced Materials (Deerfield Beach, Fla.). Feb, 2019 | Pubmed ID: 30589125 Vascularized 3D Printed Scaffolds for Promoting Bone Regeneration Biomaterials. 01, 2019 | Pubmed ID: 30415019 SF-deferoxamine, a Bone-seeking Angiogenic Drug, Prevents Bone Loss in Estrogen-deficient Mice Bone. Mar, 2019 | Pubmed ID: 30385424 An Immunological Electrospun Scaffold for Tumor Cell Killing and Healthy Tissue Regeneration Materials Horizons. Nov, 2018 | Pubmed ID: 30713696 [Research Status and Progress of Biomaterials for Bone Repair and Reconstruction] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. Jul, 2018 | Pubmed ID: 30129301 Localized Controlled Delivery of Gemcitabine Via Microsol Electrospun Fibers to Prevent Pancreatic Cancer Recurrence Advanced Healthcare Materials. Sep, 2018 | Pubmed ID: 30062854 The Inhibition of RANKL Expression in Fibroblasts Attenuate CoCr Particles Induced Aseptic Prosthesis Loosening Via the MyD88-independent TLR Signaling Pathway Biochemical and Biophysical Research Communications. 09, 2018 | Pubmed ID: 29940143 Increased 15-lipoxygenase-1 Expression in Chondrocytes Contributes to the Pathogenesis of Osteoarthritis Cell Death & Disease. Oct, 2017 | Pubmed ID: 29022900 Inflammatory MicroRNA-194 and -515 Attenuate the Biosynthesis of Chondroitin Sulfate During Human Intervertebral Disc Degeneration Oncotarget. Jul, 2017 | Pubmed ID: 28514734 Quickly Promoting Angiogenesis by Using a DFO-loaded Photo-crosslinked Gelatin Hydrogel for Diabetic Skin Regeneration Journal of Materials Chemistry. B. Jun, 2016 | Pubmed ID: 32263315 Increased EZH2 and Decreased Osteoblastogenesis During Local Irradiation-induced Bone Loss in Rats Scientific Reports. Aug, 2016 | Pubmed ID: 27499068 Reliability of Measurements on Lateral Ankle Radiographs BMC Musculoskeletal Disorders. Jul, 2016 | Pubmed ID: 27431806 Upregulating Hif-1α by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound Advanced Healthcare Materials. Apr, 2016 | Pubmed ID: 26891197 Heme Oxygenase-1 Attenuates IL-1β Induced Alteration of Anabolic and Catabolic Activities in Intervertebral Disc Degeneration Scientific Reports. Feb, 2016 | Pubmed ID: 26877238 Efficient Pd-catalyzed Domino Synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline Derivatives Organic & Biomolecular Chemistry. Oct, 2015 | Pubmed ID: 26377704 HIF-1α Disturbs Osteoblasts and Osteoclasts Coupling in Bone Remodeling by Up-regulating OPG Expression In Vitro Cellular & Developmental Biology. Animal. Sep, 2015 | Pubmed ID: 25859979 MTORC1 Maintains the Tumorigenicity of SSEA-4(+) High-grade Osteosarcoma Scientific Reports. Apr, 2015 | Pubmed ID: 25853231 Activation of HIFa Pathway in Mature Osteoblasts Disrupts the Integrity of the Osteocyte/canalicular Network PloS One. 2015 | Pubmed ID: 25806791 Circulating MicroRNA As Potential Source for Neurodegenerative Diseases Biomarkers Molecular Neurobiology. Dec, 2015 | Pubmed ID: 25367880 MicroRNA-17/20a Inhibits Glucocorticoid-induced Osteoclast Differentiation and Function Through Targeting RANKL Expression in Osteoblast Cells Bone. Nov, 2014 | Pubmed ID: 25138550 Osteoblast-secreted Factors Promote Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells Via VEGF/heme-oxygenase-1 Pathway PloS One. 2014 | Pubmed ID: 24940620 Bone Selective Protective Effect of a Novel Bone-seeking Estrogen on Trabecular Bone in Ovariectomized Rats Calcified Tissue International. Aug, 2013 | Pubmed ID: 23780350 Erythropoietin Upregulates Growth Associated Protein-43 Expression and Promotes Retinal Ganglion Cell Axonal Regeneration in Vivo After Optic Nerve Crush Neural Regeneration Research. Feb, 2012 | Pubmed ID: 25806072 IDG-SW3 Cell Culture in a Three-Dimensional Extracellular Matrix Kaizhe Chen*1, Haoyi Chen*1, Lianfu Deng1, Kai Yang1, Jin Qi1 1Department of Orthopedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine JoVE 64507 Bioengineering
IDG-SW3 Cell Culture in a Three-Dimensional Extracellular Matrix Kaizhe Chen*1, Haoyi Chen*1, Lianfu Deng1, Kai Yang1, Jin Qi1 1Department of Orthopedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine JoVE 64507 Bioengineering
