Ling-Gang Wu National Institute of Neurological Disorders and Stroke Biography Publications Institution JoVE Articles Ling-Gang Wu has not added a biography. If you are Ling-Gang Wu and would like to personalize this page please email our Author Liaison for assistance. Publications Dynamin 1 Controls Vesicle Size and Endocytosis at Hippocampal Synapses Cell Calcium. Feb, 2022 | Pubmed ID: 35220002 Clathrin-mediated Endocytosis Cooperates with Bulk Endocytosis to Generate Vesicles IScience. Feb, 2022 | Pubmed ID: 35198874 Retraction Note: Reprogramming Glioblastoma Multiforme Cells into Neurons by Protein Kinase Inhibitors Journal of Experimental & Clinical Cancer Research : CR. 11, 2021 | Pubmed ID: 34794497 Preformed Ω-profile Closure and Kiss-and-run Mediate Endocytosis and Diverse Endocytic Modes in Neuroendocrine Chromaffin Cells Neuron. 10, 2021 | Pubmed ID: 34411513 Presynaptic Kv3 Channels Are Required for Fast and Slow Endocytosis of Synaptic Vesicles Neuron. 03, 2021 | Pubmed ID: 33508244 Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis Immunity. 01, 2021 | Pubmed ID: 33220232 Vesicle Shrinking and Enlargement Play Opposing Roles in the Release of Exocytotic Contents Cell Reports. 01, 2020 | Pubmed ID: 31940486 Protein Kinase C and Calmodulin Serve As Calcium Sensors for Calcium-Stimulated Endocytosis at Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 11, 2019 | Pubmed ID: 31628181 Shisa7 is a GABA Receptor Auxiliary Subunit Controlling Benzodiazepine Actions Science (New York, N.Y.). 10, 2019 | Pubmed ID: 31601770 New Observations in Neuroscience Using Superresolution Microscopy The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 10, 2018 | Pubmed ID: 30381437 Reprogramming Glioblastoma Multiforme Cells into Neurons by Protein Kinase Inhibitors Journal of Experimental & Clinical Cancer Research : CR. Aug, 2018 | Pubmed ID: 30071868 Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis Cell. 05, 2018 | Pubmed ID: 29606354 Membrane Tension Inhibits Rapid and Slow Endocytosis in Secretory Cells Biophysical Journal. Dec, 2017 | Pubmed ID: 29211994 Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses Neuron. Dec, 2016 | Pubmed ID: 27840001 Actin Dynamics Provides Membrane Tension to Merge Fusing Vesicles into the Plasma Membrane Nature Communications. Aug, 2016 | Pubmed ID: 27576662 Hemi-fused Structure Mediates and Controls Fusion and Fission in Live Cells Nature. 06, 2016 | Pubmed ID: 27309816 α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2016 | Pubmed ID: 27098685 The Calyx of Held in the Auditory System: Structure, Function, and Development Hearing Research. Aug, 2016 | Pubmed ID: 27018297 Fusion of Lysosomes with Secretory Organelles Leads to Uncontrolled Exocytosis in the Lysosomal Storage Disease Mucolipidosis Type IV EMBO Reports. Feb, 2016 | Pubmed ID: 26682800 Suppression of Agrin-22 Production and Synaptic Dysfunction in Cln1 (-/-) Mice Annals of Clinical and Translational Neurology. Dec, 2015 | Pubmed ID: 26734660 Brain-derived Neurotrophic Factor Inhibits Calcium Channel Activation, Exocytosis, and Endocytosis at a Central Nerve Terminal The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2015 | Pubmed ID: 25788684 Erratum: Post-fusion Structural Changes and Their Roles in Exocytosis and Endocytosis of Dense-core Vesicles Nature Communications. Jan, 2015 | Pubmed ID: 25626058 Conversion of Fibroblasts to Neural Cells by P53 Depletion Cell Reports. Dec, 2014 | Pubmed ID: 25533343 Calcineurin Upregulates Local Ca(2+) Signaling Through Ryanodine Receptor-1 in Airway Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2014 | Pubmed ID: 25239916 Senescence Impairs Direct Conversion of Human Somatic Cells to Neurons Nature Communications. 2014 | Pubmed ID: 24934763 Calcineurin is Universally Involved in Vesicle Endocytosis at Neuronal and Nonneuronal Secretory Cells Cell Reports. May, 2014 | Pubmed ID: 24835995 Post-fusion Structural Changes and Their Roles in Exocytosis and Endocytosis of Dense-core Vesicles Nature Communications. 2014 | Pubmed ID: 24561832 The Yin and Yang of Calcium Effects on Synaptic Vesicle Endocytosis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2014 | Pubmed ID: 24523554 Presynaptic Glycine Receptors As a Potential Therapeutic Target for Hyperekplexia Disease Nature Neuroscience. Feb, 2014 | Pubmed ID: 24390226 Plasma Membrane Translocation of Trimerized MLKL Protein is Required for TNF-induced Necroptosis Nature Cell Biology. Jan, 2014 | Pubmed ID: 24316671 Exocytosis and Endocytosis: Modes, Functions, and Coupling Mechanisms Annual Review of Physiology. 2014 | Pubmed ID: 24274740 The SNARE Proteins SNAP25 and Synaptobrevin Are Involved in Endocytosis at Hippocampal Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2013 | Pubmed ID: 23699527 Most Vesicles in a Central Nerve Terminal Participate in Recycling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2013 | Pubmed ID: 23678124 SNARE Proteins Synaptobrevin, SNAP-25, and Syntaxin Are Involved in Rapid and Slow Endocytosis at Synapses Cell Reports. May, 2013 | Pubmed ID: 23643538 Voltage-dependent Calcium Channels at the Plasma Membrane, but Not Vesicular Channels, Couple Exocytosis to Endocytosis Cell Reports. Jun, 2012 | Pubmed ID: 22813738 Conditional Expression of Parkinson's Disease-related Mutant α-synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012 | Pubmed ID: 22764233 Calcium-channel Number Critically Influences Synaptic Strength and Plasticity at the Active Zone Nature Neuroscience. Jun, 2012 | Pubmed ID: 22683682 Cysteine String Protein α: a New Role in Vesicle Recycling Neuron. Apr, 2012 | Pubmed ID: 22500624 A Membrane Pool Retrieved Via Endocytosis Overshoot at Nerve Terminals: a Study of Its Retrieval Mechanism and Role The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2012 | Pubmed ID: 22399762 Post-tetanic Potentiation is Caused by Two Signalling Mechanisms Affecting Quantal Size and Quantal Content The Journal of Physiology. Dec, 2010 | Pubmed ID: 21041528 The Role of Calcium/calmodulin-activated Calcineurin in Rapid and Slow Endocytosis at Central Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20810903 Endocytosis and Clathrin-uncoating Defects at Synapses of Auxilin Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20160091 Rapid Endocytosis Does Not Recycle Vesicles Within the Readily Releasable Pool The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2009 | Pubmed ID: 19726662 Location Matters: Synaptotagmin Helps Place Vesicles Near Calcium Channels Neuron. Aug, 2009 | Pubmed ID: 19709623 Ca(2+) and Calmodulin Initiate All Forms of Endocytosis During Depolarization at a Nerve Terminal Nature Neuroscience. Aug, 2009 | Pubmed ID: 19633667 Small Voltage Changes at Nerve Terminals Travel Up Axons to Affect Action Potential Initiation Nature Neuroscience. May, 2009 | Pubmed ID: 19349974 Compound Vesicle Fusion Increases Quantal Size and Potentiates Synaptic Transmission Nature. May, 2009 | Pubmed ID: 19279571 GTP-independent Rapid and Slow Endocytosis at a Central Synapse Nature Neuroscience. Jan, 2008 | Pubmed ID: 18066059 Modes of Vesicle Retrieval at Ribbon Synapses, Calyx-type Synapses, and Small Central Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007 | Pubmed ID: 17978015 The Debate on the Kiss-and-run Fusion at Synapses Trends in Neurosciences. Sep, 2007 | Pubmed ID: 17765328 Rapid Bulk Endocytosis and Its Kinetics of Fission Pore Closure at a Central Synapse Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007 | Pubmed ID: 17551019 Role of Ca(2+) Channels in Short-term Synaptic Plasticity Current Opinion in Neurobiology. Jun, 2007 | Pubmed ID: 17466513 The Origin of Quantal Size Variation: Vesicular Glutamate Concentration Plays a Significant Role The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2007 | Pubmed ID: 17360928 Two Modes of Fusion Pore Opening Revealed by Cell-attached Recordings at a Synapse Nature. Nov, 2006 | Pubmed ID: 17065984 Activity-dependent Acceleration of Endocytosis at a Central Synapse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2005 | Pubmed ID: 16354926 The Decrease in the Presynaptic Calcium Current is a Major Cause of Short-term Depression at a Calyx-type Synapse Neuron. May, 2005 | Pubmed ID: 15944131 Kinetic Regulation of Vesicle Endocytosis at Synapses Trends in Neurosciences. Sep, 2004 | Pubmed ID: 15331237 Isoflurane Inhibits Transmitter Release and the Presynaptic Action Potential Anesthesiology. Mar, 2004 | Pubmed ID: 15108983 Capacitance Measurements at the Calyx of Held in the Medial Nucleus of the Trapezoid Body Journal of Neuroscience Methods. Apr, 2004 | Pubmed ID: 15003378 Single and Multiple Vesicle Fusion Induce Different Rates of Endocytosis at a Central Synapse Nature. May, 2002 | Pubmed ID: 12037569 Confocal Microscopy to Measure Three Modes of Fusion Pore Dynamics in Adrenal Chromaffin Cells Sue Han*1, Xin Wang*1, Nicholas Cordero1, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke JoVE 63569 Neuroscience Measuring Synaptic Vesicle Endocytosis in Cultured Hippocampal Neurons Seth Villarreal1, Sung Hoon Lee1,2, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke, 2College of Pharmacy, Chung-ang University JoVE 55862 Neuroscience Methods for Patch Clamp Capacitance Recordings from the Calyx Kenneth Paradiso1, Wei Wu1, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke, National Institute of Health JoVE 244 Biology
Confocal Microscopy to Measure Three Modes of Fusion Pore Dynamics in Adrenal Chromaffin Cells Sue Han*1, Xin Wang*1, Nicholas Cordero1, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke JoVE 63569 Neuroscience
Measuring Synaptic Vesicle Endocytosis in Cultured Hippocampal Neurons Seth Villarreal1, Sung Hoon Lee1,2, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke, 2College of Pharmacy, Chung-ang University JoVE 55862 Neuroscience
Methods for Patch Clamp Capacitance Recordings from the Calyx Kenneth Paradiso1, Wei Wu1, Ling-Gang Wu1 1National Institute of Neurological Disorders and Stroke, National Institute of Health JoVE 244 Biology