Patrick Van Dijck Department of Molecular Microbiology, Laboratory of Molecular Cell Biology Institute of Botany and Microbiology, VIB, KU Leuven Biography Publications Institution JoVE Articles Patrick Van Dijck has not added a biography. If you are Patrick Van Dijck and would like to personalize this page please email our Author Liaison for assistance. Publications Force Nanoscopy of Hydrophobic Interactions in the Fungal Pathogen Candida Glabrata ACS Nano. Jan, 2015 | Pubmed ID: 25621738 Clinical Implications of Oral Candidiasis: Host Tissue Damage and Disseminated Bacterial Disease Infection and Immunity. Feb, 2015 | Pubmed ID: 25422264 TREHALOSE-6-PHOSPHATE SYNTHASE 1 is Not the Only Active TPS in Arabidopsis Thaliana The Biochemical Journal. Dec, 2014 | Pubmed ID: 25495218 In Vivo Candida Glabrata Biofilm Development on Foreign Bodies in a Rat Subcutaneous Model The Journal of Antimicrobial Chemotherapy. Nov, 2014 | Pubmed ID: 25406296 Oral Administration of the Broad-spectrum Antibiofilm Compound Toremifene Inhibits Candida Albicans and Staphylococcus Aureus Biofilm Formation in Vivo Antimicrobial Agents and Chemotherapy. Dec, 2014 | Pubmed ID: 25288093 Functional Screening of a CDNA Library from the Desiccation-tolerant Plant Selaginella Lepidophylla in Yeast Mutants Identifies Trehalose Biosynthesis Genes of Plant and Microbial Origin Journal of Plant Research. Nov, 2014 | Pubmed ID: 25246071 Duplication of a Promiscuous Transcription Factor Drives the Emergence of a New Regulatory Network Nature Communications. 2014 | Pubmed ID: 25204769 Ascorbic Acid Inhibition of Candida Albicans Hsp90-mediated Morphogenesis Occurs Via the Transcriptional Regulator Upc2 Eukaryotic Cell. Oct, 2014 | Pubmed ID: 25084864 The Desiccation Tolerant Secrets of Selaginella Lepidophylla: What We Have Learned So Far? Plant Physiology and Biochemistry : PPB / Société Française De Physiologie Végétale. Jul, 2014 | Pubmed ID: 24813728 Fine Tuning of Trehalose Biosynthesis and Hydrolysis As Novel Tools for the Generation of Abiotic Stress Tolerant Plants Frontiers in Plant Science. 2014 | Pubmed ID: 24782885 Microbial Biofilms--the Coming of Age of a Research Field Pathogens and Disease. Apr, 2014 | Pubmed ID: 24723464 Trehalose Metabolism in Plants The Plant Journal : for Cell and Molecular Biology. Aug, 2014 | Pubmed ID: 24645920 Molecular Mechanisms of Antimicrobial Tolerance and Resistance in Bacterial and Fungal Biofilms Trends in Microbiology. Jun, 2014 | Pubmed ID: 24598086 Microbial Cell Surface Proteins and Secreted Metabolites Involved in Multispecies Biofilms Pathogens and Disease. Apr, 2014 | Pubmed ID: 24376219 Bioluminescence Imaging of Fungal Biofilm Development in Live Animals Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24166376 Towards Non-invasive Monitoring of Pathogen-host Interactions During Candida Albicans Biofilm Formation Using in Vivo Bioluminescence Cellular Microbiology. Jan, 2014 | Pubmed ID: 23962311 Quantifying the Forces Driving Cell-cell Adhesion in a Fungal Pathogen Langmuir : the ACS Journal of Surfaces and Colloids. Nov, 2013 | Pubmed ID: 24152214 Single-cell Force Spectroscopy of the Medically Important Staphylococcus Epidermidis-Candida Albicans Interaction Nanoscale. Nov, 2013 | Pubmed ID: 24057018 Recent Insights into Candida Albicans Biofilm Resistance Mechanisms Current Genetics. Nov, 2013 | Pubmed ID: 23974350 Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions PLoS Pathogens. Aug, 2013 | Pubmed ID: 23966851 Mammalian Ribosomal and Chaperone Protein RPS3A Counteracts α-synuclein Aggregation and Toxicity in a Yeast Model System The Biochemical Journal. Nov, 2013 | Pubmed ID: 23924367 Metabolic Engineering of Kluyveromyces Lactis for L-ascorbic Acid (vitamin C) Biosynthesis Microbial Cell Factories. 2013 | Pubmed ID: 23799937 Activities of Systemically Administered Echinocandins Against in Vivo Mature Candida Albicans Biofilms Developed in a Rat Subcutaneous Model Antimicrobial Agents and Chemotherapy. May, 2013 | Pubmed ID: 23403433 Overexpression of the Trehalase Gene AtTRE1 Leads to Increased Drought Stress Tolerance in Arabidopsis and is Involved in Abscisic Acid-induced Stomatal Closure Plant Physiology. Mar, 2013 | Pubmed ID: 23341362 Redundant and Non-redundant Roles of the Trehalose-6-phosphate Phosphatases in Leaf Growth, Root Hair Specification and Energy-responses in Arabidopsis Plant Signaling & Behavior. Mar, 2013 | Pubmed ID: 23299328 Single-molecule Imaging and Functional Analysis of Als Adhesins and Mannans During Candida Albicans Morphogenesis ACS Nano. Dec, 2012 | Pubmed ID: 23145462 The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the in Vivo Activity of Caspofungin Against Candida Albicans Biofilms The Journal of Infectious Diseases. Dec, 2012 | Pubmed ID: 22984120 Loss-of-function Mutations in HINT1 Cause Axonal Neuropathy with Neuromyotonia Nature Genetics. Oct, 2012 | Pubmed ID: 22961002 Tight Control of Trehalose Content is Required for Efficient Heat-induced Cell Elongation in Candida Albicans The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22952228 Expansive Evolution of the Trehalose-6-phosphate Phosphatase Gene Family in Arabidopsis Plant Physiology. Oct, 2012 | Pubmed ID: 22855938 Diversity in Genetic in Vivo Methods for Protein-protein Interaction Studies: from the Yeast Two-hybrid System to the Mammalian Split-luciferase System Microbiology and Molecular Biology Reviews : MMBR. Jun, 2012 | Pubmed ID: 22688816 The Heat-induced Molecular Disaggregase Hsp104 of Candida Albicans Plays a Role in Biofilm Formation and Pathogenicity in a Worm Infection Model Eukaryotic Cell. Aug, 2012 | Pubmed ID: 22635920 Potent Synergistic Effect of Doxycycline with Fluconazole Against Candida Albicans is Mediated by Interference with Iron Homeostasis Antimicrobial Agents and Chemotherapy. Jul, 2012 | Pubmed ID: 22564841 Transcription Factor Efg1 Contributes to the Tolerance of Candida Albicans Biofilms Against Antifungal Agents in Vitro and in Vivo Journal of Medical Microbiology. Jun, 2012 | Pubmed ID: 22422573 Heterozygous Missense Mutations in SMARCA2 Cause Nicolaides-Baraitser Syndrome Nature Genetics. Apr, 2012 | Pubmed ID: 22366787 Candida Biofilms and the Host: Models and New Concepts for Eradication International Journal of Microbiology. 2012 | Pubmed ID: 22164167 How Do Sugars Regulate Plant Growth? Frontiers in Plant Science. 2011 | Pubmed ID: 22629265 The Candida Albicans GAP Gene Family Encodes Permeases Involved in General and Specific Amino Acid Uptake and Sensing Eukaryotic Cell. Sep, 2011 | Pubmed ID: 21764911 Detailed Comparison of Candida Albicans and Candida Glabrata Biofilms Under Different Conditions and Their Susceptibility to Caspofungin and Anidulafungin Journal of Medical Microbiology. Sep, 2011 | Pubmed ID: 21566087 Stress Tolerance of the Saccharomyces Cerevisiae Adenylate Cyclase Fil1 (CYR1) Mutant Depends on Hsp26 Journal of Molecular Microbiology and Biotechnology. 2010 | Pubmed ID: 20924200 Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory and Autonomic Neuropathy Type I American Journal of Human Genetics. Oct, 2010 | Pubmed ID: 20920666 A CUG Codon Adapted Two-hybrid System for the Pathogenic Fungus Candida Albicans Nucleic Acids Research. Oct, 2010 | Pubmed ID: 20719741 In Vivo Efficacy of Anidulafungin Against Mature Candida Albicans Biofilms in a Novel Rat Model of Catheter-associated Candidiasis Antimicrobial Agents and Chemotherapy. Oct, 2010 | Pubmed ID: 20660685 Candida Albicans Pde1p and Gpa2p Comprise a Regulatory Module Mediating Agonist-induced CAMP Signalling and Environmental Adaptation Fungal Genetics and Biology : FG & B. Sep, 2010 | Pubmed ID: 20558315 Real-time PCR Expression Profiling of Genes Encoding Potential Virulence Factors in Candida Albicans Biofilms: Identification of Model-dependent and -independent Gene Expression BMC Microbiology. 2010 | Pubmed ID: 20398368 A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-like Proteins in Arabidopsis Molecular Plant. Mar, 2010 | Pubmed ID: 20100798 Candida Albicans Biofilm Formation in a New in Vivo Rat Model Microbiology (Reading, England). Mar, 2010 | Pubmed ID: 19959578 The Cytophaga Hutchinsonii ChTPSP: First Characterized Bifunctional TPS-TPP Protein As Putative Ancestor of All Eukaryotic Trehalose Biosynthesis Proteins Molecular Biology and Evolution. Feb, 2010 | Pubmed ID: 19812028 Nutrient Sensing G Protein-coupled Receptors: Interesting Targets for Antifungals? Medical Mycology. Nov, 2009 | Pubmed ID: 19888799 Small G Proteins in Peroxisome Biogenesis: the Potential Involvement of ADP-ribosylation Factor 6 BMC Cell Biology. 2009 | Pubmed ID: 19686593 Dominant Mutations in the Tyrosyl-tRNA Synthetase Gene Recapitulate in Drosophila Features of Human Charcot-Marie-Tooth Neuropathy Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009 | Pubmed ID: 19561293 Extensive Expression Regulation and Lack of Heterologous Enzymatic Activity of the Class II Trehalose Metabolism Proteins from Arabidopsis Thaliana Plant, Cell & Environment. Aug, 2009 | Pubmed ID: 19344332 Extracting Expression Modules from Perturbational Gene Expression Compendia BMC Systems Biology. 2008 | Pubmed ID: 18402676 Identification of Hexose Transporter-like Sensor HXS1 and Functional Hexose Transporter HXT1 in the Methylotrophic Yeast Hansenula Polymorpha Eukaryotic Cell. Apr, 2008 | Pubmed ID: 18310355 Flavour Formation in Fungi: Characterisation of KlAtf, the Kluyveromyces Lactis Orthologue of the Saccharomyces Cerevisiae Alcohol Acetyltransferases Atf1 and Atf2 Applied Microbiology and Biotechnology. Apr, 2008 | Pubmed ID: 18309479 Combined Inactivation of the Candida Albicans GPR1 and TPS2 Genes Results in Avirulence in a Mouse Model for Systemic Infection Infection and Immunity. Apr, 2008 | Pubmed ID: 18268028 A Bifunctional TPS-TPP Enzyme from Yeast Confers Tolerance to Multiple and Extreme Abiotic-stress Conditions in Transgenic Arabidopsis Planta. Nov, 2007 | Pubmed ID: 17628825 Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida Albicans Microbiology and Molecular Biology Reviews : MMBR. Jun, 2007 | Pubmed ID: 17554048 Improved Drought Tolerance Without Undesired Side Effects in Transgenic Plants Producing Trehalose Plant Molecular Biology. Jul, 2007 | Pubmed ID: 17453154 Isolation and Characterization of Brewer's Yeast Variants with Improved Fermentation Performance Under High-gravity Conditions Applied and Environmental Microbiology. Feb, 2007 | Pubmed ID: 17158628 ABI4 Mediates the Effects of Exogenous Trehalose on Arabidopsis Growth and Starch Breakdown Plant Molecular Biology. Jan, 2007 | Pubmed ID: 17031512 Water Channels Are Important for Osmotic Adjustments of Yeast Cells at Low Temperature Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622068 Disrupted Function and Axonal Distribution of Mutant Tyrosyl-tRNA Synthetase in Dominant Intermediate Charcot-Marie-Tooth Neuropathy Nature Genetics. Feb, 2006 | Pubmed ID: 16429158 Why Do Microorganisms Have Aquaporins? Trends in Microbiology. Feb, 2006 | Pubmed ID: 16406529 The Saccharomyces Cerevisiae EHT1 and EEB1 Genes Encode Novel Enzymes with Medium-chain Fatty Acid Ethyl Ester Synthesis and Hydrolysis Capacity The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16361250 Trehalose-6-phosphate Synthase As an Intrinsic Selection Marker for Plant Transformation Journal of Biotechnology. Feb, 2006 | Pubmed ID: 16271790 Heterologous Aquaporin (AQY2-1) Expression Strongly Enhances Freeze Tolerance of Schizosaccharomyces Pombe Journal of Molecular Microbiology and Biotechnology. 2005 | Pubmed ID: 16254446 Aquaporin Expression and Freeze Tolerance in Candida Albicans Applied and Environmental Microbiology. Oct, 2005 | Pubmed ID: 16204575 The G Protein-coupled Receptor Gpr1 and the Galpha Protein Gpa2 Act Through the CAMP-protein Kinase A Pathway to Induce Morphogenesis in Candida Albicans Molecular Biology of the Cell. Apr, 2005 | Pubmed ID: 15673611 The Arabidopsis Trehalose-6-P Synthase AtTPS1 Gene is a Regulator of Glucose, Abscisic Acid, and Stress Signaling Plant Physiology. Nov, 2004 | Pubmed ID: 15516499 Glucose and Sucrose Act As Agonist and Mannose As Antagonist Ligands of the G Protein-coupled Receptor Gpr1 in the Yeast Saccharomyces Cerevisiae Molecular Cell. Oct, 2004 | Pubmed ID: 15494315 Glucose and Sucrose: Hazardous Fast-food for Industrial Yeast? Trends in Biotechnology. Oct, 2004 | Pubmed ID: 15450747 New Selection Marker for Plant Transformation Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15269438 Aquaporin-mediated Improvement of Freeze Tolerance of Saccharomyces Cerevisiae is Restricted to Rapid Freezing Conditions Applied and Environmental Microbiology. Jun, 2004 | Pubmed ID: 15184134 The High General Stress Resistance of the Saccharomyces Cerevisiae Fil1 Adenylate Cyclase Mutant (Cyr1Lys1682) is Only Partially Dependent on Trehalose, Hsp104 and Overexpression of Msn2/4-regulated Genes Yeast (Chichester, England). Jan, 2004 | Pubmed ID: 14745784 Determinants of Freeze Tolerance in Microorganisms, Physiological Importance, and Biotechnological Applications Advances in Applied Microbiology. 2003 | Pubmed ID: 14696318 Multi-level Response of the Yeast Genome to Glucose Genome Biology. 2003 | Pubmed ID: 14611650 Progress in Functional Genomics Approaches to Antifungal Drug Target Discovery Trends in Microbiology. Oct, 2003 | Pubmed ID: 14557030 Uncoupling of the Glucose Growth Defect and the Deregulation of Glycolysis in Saccharomyces Cerevisiae Tps1 Mutants Expressing Trehalose-6-phosphate-insensitive Hexokinase from Schizosaccharomyces Pombe Biochimica Et Biophysica Acta. Sep, 2003 | Pubmed ID: 14507429 Activation State of Protein Kinase A As Measured in Permeabilised Saccharomyces Cerevisiae Cells Correlates with PKA-controlled Phenotypes in Vivo FEMS Yeast Research. Mar, 2003 | Pubmed ID: 12702255 Aquaporin Expression Correlates with Freeze Tolerance in Baker's Yeast, and Overexpression Improves Freeze Tolerance in Industrial Strains Applied and Environmental Microbiology. Dec, 2002 | Pubmed ID: 12450819 Isolation and Characterization of a Freeze-tolerant Diploid Derivative of an Industrial Baker's Yeast Strain and Its Use in Frozen Doughs Applied and Environmental Microbiology. Oct, 2002 | Pubmed ID: 12324320 Functional Genomics Approaches for the Identification and Validation of Antifungal Drug Targets American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice. 2002 | Pubmed ID: 12083946 Truncation of Arabidopsis Thaliana and Selaginella Lepidophylla Trehalose-6-phosphate Synthase Unlocks High Catalytic Activity and Supports High Trehalose Levels on Expression in Yeast The Biochemical Journal. Aug, 2002 | Pubmed ID: 11978181 Disruption of the Candida Albicans TPS2 Gene Encoding Trehalose-6-phosphate Phosphatase Decreases Infectivity Without Affecting Hypha Formation Infection and Immunity. Apr, 2002 | Pubmed ID: 11895938 Candida albicans Biofilm Udvikling om medicinsk relevante fremmedlegemer i en mus Subkutan Model Efterfulgt af Bioluminescens Imaging Soňa Kucharíková1, Greetje Vande Velde2, Uwe Himmelreich2, Patrick Van Dijck1 1Department of Molecular Microbiology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, VIB, KU Leuven, 2Biomedical MRI Unit/ MoSAIC, Department of Imaging & Pathology, KU Leuven Medicine
Candida albicans Biofilm Udvikling om medicinsk relevante fremmedlegemer i en mus Subkutan Model Efterfulgt af Bioluminescens Imaging Soňa Kucharíková1, Greetje Vande Velde2, Uwe Himmelreich2, Patrick Van Dijck1 1Department of Molecular Microbiology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, VIB, KU Leuven, 2Biomedical MRI Unit/ MoSAIC, Department of Imaging & Pathology, KU Leuven Medicine