Paul Wilmes Luxembourg Centre for Systems Biomedicine University of Luxembourg Biography Publications Institution JoVE Articles Paul Wilmes has not added a biography. If you are Paul Wilmes and would like to personalize this page please email our Author Liaison for assistance. Publications Spatio-functional Organization in Virocells of Small Uncultivated Archaea from the Deep Biosphere The ISME Journal. Jul, 2023 | Pubmed ID: 37468677 Lower Gastric Sensitivity in Quiescent Inflammatory Bowel Disease Than in Irritable Bowel Syndrome Physiology & Behavior. Jul, 2023 | Pubmed ID: 37468056 Reservoirs of Antimicrobial Resistance in the Context of One Health Current Opinion in Microbiology. Jun, 2023 | Pubmed ID: 36913905 Altered Infective Competence of the Human Gut Microbiome in COVID-19 Microbiome. Mar, 2023 | Pubmed ID: 36894986 Glacier-Fed Stream Biofilms Harbor Diverse Resistomes and Biosynthetic Gene Clusters Microbiology Spectrum. Feb, 2023 | Pubmed ID: 36688698 Alterations of Oral Microbiota and Impact on the Gut Microbiome in Type 1 Diabetes Mellitus Revealed by Integrated multi-omic Analyses Microbiome. Dec, 2022 | Pubmed ID: 36578059 Long COVID Classification: Findings from a Clustering Analysis in the Predi-COVID Cohort Study International Journal of Environmental Research and Public Health. Nov, 2022 | Pubmed ID: 36498091 Binny: an Automated Binning Algorithm to Recover High-quality Genomes from Complex Metagenomic Datasets Briefings in Bioinformatics. Nov, 2022 | Pubmed ID: 36239393 Disease Progression, Resilience, and Inflammation Markers During the Coronavirus Disease 2019 Pandemic in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2022 | Pubmed ID: 36148927 Mobilome-driven Segregation of the Resistome in Biological Wastewater Treatment ELife. Sep, 2022 | Pubmed ID: 36111782 SnapShot: The Expobiome Map Cell Host & Microbe. Sep, 2022 | Pubmed ID: 36108614 The Gut Microbiome Molecular Complex in Human Health and Disease Cell Host & Microbe. Sep, 2022 | Pubmed ID: 36108612 Long COVID Symptomatology After 12 Months and Its Impact on Quality of Life According to Initial Coronavirus Disease 2019 Disease Severity Open Forum Infectious Diseases. Aug, 2022 | Pubmed ID: 35983269 Studying the Parkinson's Disease Metabolome and Exposome in Biological Samples Through Different Analytical and Cheminformatics Approaches: a Pilot Study Analytical and Bioanalytical Chemistry. Oct, 2022 | Pubmed ID: 35829770 The Microbiome of Cryospheric Ecosystems Nature Communications. Jun, 2022 | Pubmed ID: 35655063 Evolution of the Murine Gut Resistome Following Broad-spectrum Antibiotic Treatment Nature Communications. Apr, 2022 | Pubmed ID: 35484157 Combinatorial Analysis Reveals Highly Coordinated Early-stage Immune Reactions That Predict Later Antiviral Immunity in Mild COVID-19 Patients Cell Reports. Medicine. Apr, 2022 | Pubmed ID: 35480624 Toward Hypothesis-driven, Personalized Microbiome Screening Cell Reports Methods. Jan, 2022 | Pubmed ID: 35474872 Genomic and Metabolic Adaptations of Biofilms to Ecological Windows of Opportunity in Glacier-fed Streams Nature Communications. Apr, 2022 | Pubmed ID: 35444202 The Gut Microbial Metabolite Formate Exacerbates Colorectal Cancer Progression Nature Metabolism. Apr, 2022 | Pubmed ID: 35437333 Glacier Shrinkage Will Accelerate Downstream Decomposition of Organic Matter and Alters Microbiome Structure and Function Global Change Biology. Jun, 2022 | Pubmed ID: 35320603 The Benefits, Costs and Feasibility of a Low Incidence COVID-19 Strategy The Lancet Regional Health. Europe. Feb, 2022 | Pubmed ID: 35005678 Microdiversity Characterizes Prevalent Phylogenetic Clades in the Glacier-fed Stream Microbiome The ISME Journal. Mar, 2022 | Pubmed ID: 34522009 Persistence of Birth Mode-dependent Effects on Gut Microbiome Composition, Immune System Stimulation and Antimicrobial Resistance During the First Year of Life ISME Communications. Mar, 2021 | Pubmed ID: 36717704 Systematic Characterization of Human Gut Microbiome-secreted Molecules by Integrated Multi-omics ISME Communications. Dec, 2021 | Pubmed ID: 35106519 The Metaproteomics Initiative: a Coordinated Approach for Propelling the Functional Characterization of Microbiomes Microbiome. Dec, 2021 | Pubmed ID: 34930457 Critical Assessment of MetaProteome Investigation (CAMPI): a Multi-laboratory Comparison of Established Workflows Nature Communications. Dec, 2021 | Pubmed ID: 34911965 Reporting Guidelines for Human Microbiome Research: the STORMS Checklist Nature Medicine. Nov, 2021 | Pubmed ID: 34789871 Emulating the Gut-liver Axis: Dissecting the Microbiome's Effect on Drug Metabolism Using Multiorgan-on-chip Models Current Opinion in Endocrine and Metabolic Research. Jun, 2021 | Pubmed ID: 34239997 Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies Frontiers in Genetics. 2021 | Pubmed ID: 34194470 Mantis: Flexible and Consensus-driven Genome Annotation GigaScience. Jun, 2021 | Pubmed ID: 34076241 SARS-CoV-2 Transmission Risk from Asymptomatic Carriers: Results from a Mass Screening Programme in Luxembourg The Lancet Regional Health. Europe. May, 2021 | Pubmed ID: 33997830 Unification of Functional Annotation Descriptions Using Text Mining Biological Chemistry. Jul, 2021 | Pubmed ID: 33984880 SARS-CoV-2 Transmission in Educational Settings During an Early Summer Epidemic Wave in Luxembourg, 2020 BMC Infectious Diseases. May, 2021 | Pubmed ID: 33947340 Generalisation of COVID-19 Incidences Provides a Biased View of the Actual Epidemiological Situation The Lancet Regional Health. Europe. Jun, 2021 | Pubmed ID: 33937902 PathoFact: a Pipeline for the Prediction of Virulence Factors and Antimicrobial Resistance Genes in Metagenomic Data Microbiome. Feb, 2021 | Pubmed ID: 33597026 Roles of Bacteriophages, Plasmids and CRISPR Immunity in Microbial Community Dynamics Revealed Using Time-series Integrated Meta-omics Nature Microbiology. Jan, 2021 | Pubmed ID: 33139880 IgE-Mediated Peanut Allergy: Current and Novel Predictive Biomarkers for Clinical Phenotypes Using Multi-Omics Approaches Frontiers in Immunology. 2020 | Pubmed ID: 33584660 Extracellular Vesicles Modulate Gut Epithelial Cell Innate Immunity FomA and TLR2 Frontiers in Immunology. 2020 | Pubmed ID: 33408714 Patterns and Drivers of Extracellular Enzyme Activity in New Zealand Glacier-Fed Streams Frontiers in Microbiology. 2020 | Pubmed ID: 33329472 Dichloromethane Degradation Pathway from Unsequenced Sp. MC8b Rapidly Explored by Pan-Proteomics Microorganisms. Nov, 2020 | Pubmed ID: 33260855 Optimised Biomolecular Extraction for Metagenomic Analysis of Microbial Biofilms from High-mountain Streams PeerJ. 2020 | Pubmed ID: 33194372 Integration of Time-series Meta-omics Data Reveals How Microbial Ecosystems Respond to Disturbance Nature Communications. Oct, 2020 | Pubmed ID: 33077707 Systems Biology of Acidophile Biofilms for Efficient Metal Extraction Scientific Data. Jul, 2020 | Pubmed ID: 32636389 Publisher Correction: Building an International Consortium for Tracking Coronavirus Health Status Nature Medicine. Aug, 2020 | Pubmed ID: 32591764 Compositional and Functional Characterisation of Biomass-degrading Microbial Communities in Guts of Plant Fibre- and Soil-feeding Higher Termites Microbiome. Jun, 2020 | Pubmed ID: 32576253 Building an International Consortium for Tracking Coronavirus Health Status Nature Medicine. Aug, 2020 | Pubmed ID: 32488218 Integrative Omics Analysis of the Termite Gut System Adaptation to Miscanthus Diet Identifies Lignocellulose Degradation Enzymes Communications Biology. Jun, 2020 | Pubmed ID: 32483294 Correction To: Genetic and Metabolic Links Between the Murine Microbiome and Memory Microbiome. May, 2020 | Pubmed ID: 32466793 Genetic and Metabolic Links Between the Murine Microbiome and Memory Microbiome. Apr, 2020 | Pubmed ID: 32299497 Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism? Trends in Microbiology. May, 2020 | Pubmed ID: 32298617 Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32232038 Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function Cell Metabolism. May, 2020 | Pubmed ID: 32213345 Correction for Bellenberg Et Al., "Automated Microscopic Analysis of Metal Sulfide Colonization by Acidophilic Microorganisms" Applied and Environmental Microbiology. Jan, 2020 | Pubmed ID: 31964679 Reverse Engineering Directed Gene Regulatory Networks from Transcriptomics and Proteomics Data of Biomining Bacterial Communities with Approximate Bayesian Computation and Steady-state Signalling Simulations BMC Bioinformatics. Jan, 2020 | Pubmed ID: 31964336 The Microbiome-gut-brain Axis in Acute and Chronic Brain Diseases Current Opinion in Neurobiology. Apr, 2020 | Pubmed ID: 31812830 Sample Preservation and Storage Significantly Impact Taxonomic and Functional Profiles in Metaproteomics Studies of the Human Gut Microbiome Microorganisms. Sep, 2019 | Pubmed ID: 31546776 Connecting Environmental Exposure and Neurodegeneration Using Cheminformatics and High Resolution Mass Spectrometry: Potential and Challenges Environmental Science. Processes & Impacts. Sep, 2019 | Pubmed ID: 31305828 Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells Cell Reports. Apr, 2019 | Pubmed ID: 31042485 Deep Neural Networks Outperform Human Expert's Capacity in Characterizing Bioleaching Bacterial Biofilm Composition Biotechnology Reports (Amsterdam, Netherlands). Jun, 2019 | Pubmed ID: 30949441 The Gut Microbiota and Hematopoietic Stem Cell Transplantation: Challenges and Potentials Journal of Innate Immunity. 2019 | Pubmed ID: 30286447 Weak Iron Oxidation by Maintains a Favorable Redox Potential for Chalcopyrite Bioleaching Frontiers in Microbiology. 2018 | Pubmed ID: 30631311 Birth Mode is Associated with Earliest Strain-conferred Gut Microbiome Functions and Immunostimulatory Potential Nature Communications. Nov, 2018 | Pubmed ID: 30504906 Dark Matter in Host-microbiome Metabolomics: Tackling the Unknowns-A Review Analytica Chimica Acta. Dec, 2018 | Pubmed ID: 30292286 Expanding the Use of Spectral Libraries in Proteomics Journal of Proteome Research. Dec, 2018 | Pubmed ID: 30270626 Sequential Isolation of DNA, RNA, Protein, and Metabolite Fractions from Murine Organs and Intestinal Contents for Integrated Omics of Host-Microbiota Interactions Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30259493 The RNA Complement of Outer Membrane Vesicles From Serovar Typhimurium Under Distinct Culture Conditions Frontiers in Microbiology. 2018 | Pubmed ID: 30214435 Expressed Protein Profile of a Tectomicrobium and Other Microbial Symbionts in the Marine Sponge Aplysina Aerophoba As Evidenced by Metaproteomics Scientific Reports. Aug, 2018 | Pubmed ID: 30087358 Automated Microscopic Analysis of Metal Sulfide Colonization by Acidophilic Microorganisms Applied and Environmental Microbiology. 10, 2018 | Pubmed ID: 30076195 A Year of Monitoring 20 Mesophilic Full-scale Bioreactors Reveals the Existence of Stable but Different Core Microbiomes in Bio-waste and Wastewater Anaerobic Digestion Systems Biotechnology for Biofuels. 2018 | Pubmed ID: 30038663 Resolving Host-microbe Interactions in the Gut: the Promise of in Vitro Models to Complement in Vivo Research Current Opinion in Microbiology. Aug, 2018 | Pubmed ID: 30031243 Small RNA Profiling of Low Biomass Samples: Identification and Removal of Contaminants BMC Biology. May, 2018 | Pubmed ID: 29759067 Extraction and Analysis of RNA Isolated from Pure Bacteria-Derived Outer Membrane Vesicles Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29484596 Human Gut Microbiome: Function Matters Trends in Microbiology. Jul, 2018 | Pubmed ID: 29173869 Multi-omics Reveals the Lifestyle of the Acidophilic, Mineral-Oxidizing Model Species Leptospirillum Ferriphilum Applied and Environmental Microbiology. 02, 2018 | Pubmed ID: 29150517 Measuring Soil Sustainability Via Soil Resilience The Science of the Total Environment. Jun, 2018 | Pubmed ID: 29054651 The Nasal and Gut Microbiome in Parkinson's Disease and Idiopathic Rapid Eye Movement Sleep Behavior Disorder Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2018 | Pubmed ID: 28843021 First Draft Genome Sequence of a Strain Belonging to the Genus and Its Gene Expression in Situ Standards in Genomic Sciences. 2017 | Pubmed ID: 29075368 Ninety-nine De Novo Assembled Genomes from the Moose (Alces Alces) Rumen Microbiome Provide New Insights into Microbial Plant Biomass Degradation The ISME Journal. Nov, 2017 | Pubmed ID: 28731473 Integrated Meta-omic Analyses of the Gastrointestinal Tract Microbiome in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation Translational Research : the Journal of Laboratory and Clinical Medicine. Aug, 2017 | Pubmed ID: 28686852 ICoVeR - an Interactive Visualization Tool for Verification and Refinement of Metagenomic Bins BMC Bioinformatics. May, 2017 | Pubmed ID: 28464793 Generation of Genome-scale Metabolic Reconstructions for 773 Members of the Human Gut Microbiota Nature Biotechnology. Jan, 2017 | Pubmed ID: 27893703 Identification, Recovery, and Refinement of Hitherto Undescribed Population-Level Genomes from the Human Gastrointestinal Tract Frontiers in Microbiology. 2016 | Pubmed ID: 27445992 Erratum To: Phenotypic Differentiation of Gastrointestinal Microbes is Reflected in Their Encoded Metabolic Repertoires Microbiome. Jul, 2016 | Pubmed ID: 27377779 Sources and Functions of Extracellular Small RNAs in Human Circulation Annual Review of Nutrition. Jul, 2016 | Pubmed ID: 27215587 A Microfluidics-based in Vitro Model of the Gastrointestinal Human-microbe Interface Nature Communications. May, 2016 | Pubmed ID: 27168102 The Human Gut Microbiome in Health: Establishment and Resilience of Microbiota over a Lifetime Environmental Microbiology. Jul, 2016 | Pubmed ID: 27059297 In Situ Phenotypic Heterogeneity Among Single Cells of the Filamentous Bacterium Candidatus Microthrix Parvicella The ISME Journal. May, 2016 | Pubmed ID: 26505828 Comparative Integrated Omics: Identification of Key Functionalities in Microbial Community-wide Metabolic Networks NPJ Biofilms and Microbiomes. 2015 | Pubmed ID: 28721231 Phenotypic Differentiation of Gastrointestinal Microbes is Reflected in Their Encoded Metabolic Repertoires Microbiome. Nov, 2015 | Pubmed ID: 26617277 A Decade of Metaproteomics: Where We Stand and What the Future Holds Proteomics. Oct, 2015 | Pubmed ID: 26315987 Integrated Omics for the Identification of Key Functionalities in Biological Wastewater Treatment Microbial Communities Microbial Biotechnology. May, 2015 | Pubmed ID: 25678254 VizBin - an Application for Reference-independent Visualization and Human-augmented Binning of Metagenomic Data Microbiome. 2015 | Pubmed ID: 25621171 The Extracellular RNA Complement of Escherichia Coli MicrobiologyOpen. Apr, 2015 | Pubmed ID: 25611733 Community-integrated Omics Links Dominance of a Microbial Generalist to Fine-tuned Resource Usage Nature Communications. Nov, 2014 | Pubmed ID: 25424998 Lipid-based Biofuel Production from Wastewater Current Opinion in Biotechnology. Dec, 2014 | Pubmed ID: 24768793 Systematic Design of 18S RRNA Gene Primers for Determining Eukaryotic Diversity in Microbial Consortia PloS One. 2014 | Pubmed ID: 24755918 Alignment-free Visualization of Metagenomic Data by Nonlinear Dimension Reduction Scientific Reports. Mar, 2014 | Pubmed ID: 24682077 A Hundred Years of Activated Sludge: Time for a Rethink Frontiers in Microbiology. 2014 | Pubmed ID: 24624120 From Meta-omics to Causality: Experimental Models for Human Microbiome Research Microbiome. May, 2013 | Pubmed ID: 24450613 Sequential Isolation of Metabolites, RNA, DNA, and Proteins from the Same Unique Sample Methods in Enzymology. 2013 | Pubmed ID: 24060123 Condensing the Omics Fog of Microbial Communities Trends in Microbiology. Jul, 2013 | Pubmed ID: 23764387 A Biomolecular Isolation Framework for Eco-systems Biology The ISME Journal. Jan, 2013 | Pubmed ID: 22763648 The Complex Exogenous RNA Spectra in Human Plasma: an Interface with Human Gut Biota? PloS One. 2012 | Pubmed ID: 23251414 Genome Sequence of "Candidatus Microthrix Parvicella" Bio17-1, a Long-chain-fatty-acid-accumulating Filamentous Actinobacterium from a Biological Wastewater Treatment Plant Journal of Bacteriology. Dec, 2012 | Pubmed ID: 23144412 A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis Catherine Sedrani1, Gemma Gomez-Giro1, Léa Grandmougin1, Jens Christian Schwamborn1, Paul Wilmes1,2 1Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 2Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg JoVE 64483 Biology
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis Catherine Sedrani1, Gemma Gomez-Giro1, Léa Grandmougin1, Jens Christian Schwamborn1, Paul Wilmes1,2 1Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 2Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg JoVE 64483 Biology