Scott Magness Department of Cell Biology and Physiology University of North Carolina at Chapel Hill Biography Publications Institution JoVE Articles Scott Magness has not added a biography. If you are Scott Magness and would like to personalize this page please email our Author Liaison for assistance. Publications Therapeutically Engineered Induced Neural Stem Cells Are Tumour-homing and Inhibit Progression of Glioblastoma Nature Communications. 2016 | Pubmed ID: 26830441 SOX9 Maintains Reserve Stem Cells and Preserves Radioresistance in Mouse Small Intestine Gastroenterology. Nov, 2015 | Pubmed ID: 26170137 IGF1 Stimulates Crypt Expansion Via Differential Activation of 2 Intestinal Stem Cell Populations FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2015 | Pubmed ID: 25837582 A High-throughput Platform for Stem Cell Niche Co-cultures and Downstream Gene Expression Analysis Nature Cell Biology. Mar, 2015 | Pubmed ID: 25664616 Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell. Dec, 2014 | Pubmed ID: 25465495 Impact of Diet-induced Obesity on Intestinal Stem Cells: Hyperproliferation but Impaired Intrinsic Function That Requires Insulin/IGF1 Endocrinology. Sep, 2014 | Pubmed ID: 24914941 Optimization of 3-D Organotypic Primary Colonic Cultures for Organ-on-chip Applications Journal of Biological Engineering. 2014 | Pubmed ID: 24690469 In Vitro Generation of Colonic Epithelium from Primary Cells Guided by Microstructures Lab on a Chip. May, 2014 | Pubmed ID: 24647645 Capture and 3D Culture of Colonic Crypts and Colonoids in a Microarray Platform Lab on a Chip. Dec, 2013 | Pubmed ID: 24113577 A Multicenter Study to Standardize Reporting and Analyses of Fluorescence-activated Cell-sorted Murine Intestinal Epithelial Cells American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2013 | Pubmed ID: 23928185 Cell Lineage Identification and Stem Cell Culture in a Porcine Model for the Study of Intestinal Epithelial Regeneration PloS One. 2013 | Pubmed ID: 23840480 Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-formation Assay Gastroenterology. Aug, 2013 | Pubmed ID: 23644405 Brief Report: CD24 and CD44 Mark Human Intestinal Epithelial Cell Populations with Characteristics of Active and Facultative Stem Cells Stem Cells (Dayton, Ohio). Sep, 2013 | Pubmed ID: 23553902 Restriction of Intestinal Stem Cell Expansion and the Regenerative Response by YAP Nature. Jan, 2013 | Pubmed ID: 23178811 Mucosal Healing and Fibrosis After Acute or Chronic Inflammation in Wild Type FVB-N Mice and C57BL6 Procollagen α1(I)-promoter-GFP Reporter Mice PloS One. 2012 | Pubmed ID: 22880035 A Nomenclature for Intestinal In Vitro Cultures American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2012 | Pubmed ID: 22461030 Activation of Two Distinct Sox9-EGFP-expressing Intestinal Stem Cell Populations During Crypt Regeneration After Irradiation American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2012 | Pubmed ID: 22361729 Mitochondrial DNA Polymerase Editing Mutation, PolgD257A, Disturbs Stem-progenitor Cell Cycling in the Small Intestine and Restricts Excess Fat Absorption American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2012 | Pubmed ID: 22345551 Notch Signaling Modulates Proliferation and Differentiation of Intestinal Crypt Base Columnar Stem Cells Development (Cambridge, England). Feb, 2012 | Pubmed ID: 22190634 Sorting Mouse Jejunal Epithelial Cells with CD24 Yields a Population with Characteristics of Intestinal Stem Cells American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2011 | Pubmed ID: 21183658 High-fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse PloS One. 2010 | Pubmed ID: 20808947 Sox9 Expression Marks a Subset of CD24-expressing Small Intestine Epithelial Stem Cells That Form Organoids in Vitro American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2010 | Pubmed ID: 20185687 Distinct SOX9 Levels Differentially Mark Stem/progenitor Populations and Enteroendocrine Cells of the Small Intestine Epithelium American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2009 | Pubmed ID: 19228882 Insulin Receptor Substrate-1 Deficiency Promotes Apoptosis in the Putative Intestinal Crypt Stem Cell Region, Limits Apcmin/+ Tumors, and Regulates Sox9 Endocrinology. Jan, 2008 | Pubmed ID: 17916629 Gnotobiotic IL-10-/-;NF-kappa B(EGFP) Mice Reveal the Critical Role of TLR/NF-kappa B Signaling in Commensal Bacteria-induced Colitis Journal of Immunology (Baltimore, Md. : 1950). May, 2007 | Pubmed ID: 17475882 SOX2 is a Dose-dependent Regulator of Retinal Neural Progenitor Competence Genes & Development. May, 2006 | Pubmed ID: 16651659 NF-kappaB Activation in Kupffer Cells After Partial Hepatectomy American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2005 | Pubmed ID: 15905413 SOX2, a Persistent Marker for Multipotential Neural Stem Cells Derived from Embryonic Stem Cells, the Embryo or the Adult Developmental Neuroscience. Mar-Aug, 2004 | Pubmed ID: 15711057 A Dual Reporter Gene Transgenic Mouse Demonstrates Heterogeneity in Hepatic Fibrogenic Cell Populations Hepatology (Baltimore, Md.). Nov, 2004 | Pubmed ID: 15389867 In Vivo Pattern of Lipopolysaccharide and Anti-CD3-induced NF-kappa B Activation Using a Novel Gene-targeted Enhanced GFP Reporter Gene Mouse Journal of Immunology (Baltimore, Md. : 1950). Aug, 2004 | Pubmed ID: 15265883 An Exon 10 Deletion in the Mouse Ferrochelatase Gene Has a Dominant-negative Effect and Causes Mild Protoporphyria Blood. Aug, 2002 | Pubmed ID: 12149233 Isolation and Characterization of Single Cells from Zebrafish Embryos Leigh Ann Samsa1,2, Nicole Fleming2,3, Scott Magness1, Li Qian2,3, Jiandong Liu2,3 1Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, 2McAllister Heart Institute, University of North Carolina at Chapel Hill, 3Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill JoVE 53877 Developmental Biology
Isolation and Characterization of Single Cells from Zebrafish Embryos Leigh Ann Samsa1,2, Nicole Fleming2,3, Scott Magness1, Li Qian2,3, Jiandong Liu2,3 1Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, 2McAllister Heart Institute, University of North Carolina at Chapel Hill, 3Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill JoVE 53877 Developmental Biology