Steven L. Carroll Hollings Cancer Center Medical University of South Carolina Biography Publications Institution JoVE Articles Steven L. Carroll has not added a biography. If you are Steven L. Carroll and would like to personalize this page please email our Author Liaison for assistance. Publications Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival The American Journal of Pathology. Sep, 2023 | Pubmed ID: 37328102 LPAR1 and Aberrantly Expressed LPAR3 Differentially Promote the Migration and Proliferation of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Mar, 2023 | Pubmed ID: 36416236 Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table Biopreservation and Biobanking. Feb, 2023 | Pubmed ID: 35507966 Developmental, Neurochemical, and Behavioral Analyses of ErbB4 Cyt-1 Knockout Mice Journal of Neurochemistry. Jun, 2022 | Pubmed ID: 35523590 The RASopathies: Biology, Genetics and Therapeutic Options Advances in Cancer Research. 2022 | Pubmed ID: 35101235 Suppression of Fli-1 Protects Against Pericyte Loss and Cognitive Deficits in Alzheimer's Disease Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2022 | Pubmed ID: 35038582 R-Ras Subfamily Proteins Elicit Distinct Physiologic Effects and Phosphoproteome Alterations in Neurofibromin-null MPNST Cells Cell Communication and Signaling : CCS. Sep, 2021 | Pubmed ID: 34530870 The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change The American Journal of Pathology. Sep, 2021 | Pubmed ID: 34111428 The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33925820 Establishment and Genomic Characterization of a Sporadic Malignant Peripheral Nerve Sheath Tumor Cell Line Scientific Reports. Mar, 2021 | Pubmed ID: 33707600 Each Patient is a Research Biorepository: Informatics-enabled Research on Surplus Clinical Specimens Via the Living BioBank Journal of the American Medical Informatics Association : JAMIA. 01, 2021 | Pubmed ID: 33166379 Chemoembolizing Hepatocellular Carcinoma with Microsphere Cored with Arsenic Trioxide Microcrystal Drug Delivery. Nov, 2020 | Pubmed ID: 33307843 Assessing Interobserver Variability and Accuracy in the Histological Diagnosis and Classification of Cutaneous Neurofibromass Neuro-oncology Advances. Jul, 2020 | Pubmed ID: 32642737 Serum Pro-BDNF Levels Correlate with Phospho-tau Staining in Alzheimer's Disease Neurobiology of Aging. 03, 2020 | Pubmed ID: 31882186 Salinomycin Targets the Genome of Radioresistant Cells in Glioblastomas Neuro-oncology. 02, 2020 | Pubmed ID: 31784742 The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699905 Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia The American Journal of Pathology. 10, 2019 | Pubmed ID: 31351986 ErbB4 Promotes Malignant Peripheral Nerve Sheath Tumor Pathogenesis Via Ras-independent Mechanisms Cell Communication and Signaling : CCS. 07, 2019 | Pubmed ID: 31291965 The Evolution and Multi-molecular Properties of NF1 Cutaneous Neurofibromas Originating from C-fiber Sensory Endings and Terminal Schwann Cells at Normal Sites of Sensory Terminations in the Skin PloS One. 2019 | Pubmed ID: 31107888 Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia Journal of Neuropathology and Experimental Neurology. 04, 2019 | Pubmed ID: 30856249 Cutaneous Neurofibromas: Current Clinical and Pathologic Issues Neurology. 07, 2018 | Pubmed ID: 29987130 Oridonin Inhibits Aberrant AKT Activation in Breast Cancer Oncotarget. May, 2018 | Pubmed ID: 29844859 Pathology of NNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease Neuroscience. 08, 2018 | Pubmed ID: 29782905 Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms Advances in Anatomic Pathology. Sep, 2018 | Pubmed ID: 29762158 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve Journal of Neuropathology and Experimental Neurology. 04, 2017 | Pubmed ID: 28340093 BH3 Mimetics Suppress CXCL12 Expression in Human Malignant Peripheral Nerve Sheath Tumor Cells Oncotarget. Jan, 2017 | Pubmed ID: 28055968 Neuronal Exosomes Reveal Alzheimer's Disease Biomarkers in Down Syndrome Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27755974 Current Status and Recommendations for Biomarkers and Biobanking in Neurofibromatosis Neurology. Aug, 2016 | Pubmed ID: 27527649 STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells Molecular Cancer Research : MCR. 05, 2016 | Pubmed ID: 26883073 The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors As a Paradigm for Cross-Species Comparative Oncogenomics The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26740486 Classic Ras Proteins Promote Proliferation and Survival Via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells Journal of Neuropathology and Experimental Neurology. Jun, 2015 | Pubmed ID: 25946318 Combinatorial Therapy with Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289889 Gemeinsame Genetische Varianten in Der CLDN2 Und PRSS1-PRSS2 Loci ändern Risiko Für Alkoholbedingte Und Sporadische Pankreatitis Nature Genetics. Nov, 2012 | Pubmed ID: 23143602 Die Pfanne ErbB-Inhibitor PD168393 Verbessert Die Lysosomale Dysfunktion-induzierte Apoptotic Tod in Maligner Peripherer Nerven Scheide Tumorzellen Neuro-oncology. Jan, 2012 | Pubmed ID: 22259051 Molekulare Mechanismen Die Pathogenese Der Schwann-Zelle Tumoren Fördern Acta Neuropathologica. Dec, 2011 | Pubmed ID: 22160322 Gentechnisch Veränderte Mausmodelle Werfen Ein Neues Licht Auf Die Pathogenese Der Neurofibromatose Typ Ich-bezogenen Tumoren Des Peripheren Nervensystems Brain Research Bulletin. Aug, 2011 | Pubmed ID: 21855613 Gemeinsame Varianten Bei MS4A4/MS4A6E, CD2AP, CD33 Und EPHA1 Sind Spät Beginnende Alzheimer-Krankheit Zugeordnet Nature Genetics. May, 2011 | Pubmed ID: 21460841 Tamoxifen Hemmt Maligner Peripherer Nerven Scheide Tumor Auf Östrogen-Rezeptor-unabhängigen Weise Neuro-oncology. Jan, 2011 | Pubmed ID: 21075781 Gemeinsame Varianten Um 7 P 21 Sind Lobäres Frontotemporale Degeneration Mit TDP-43 Einschlüsse Zugeordnet Nature Genetics. Mar, 2010 | Pubmed ID: 20154673 Neuregulin-1 Beta and Neuregulin-1 Alpha Differentially Affect the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Nov, 2009 | Pubmed ID: 19306381 Wie Funktioniert Die Schwann-Zelle-Linie Form Tumoren Im NF1? Glia. Nov, 2008 | Pubmed ID: 18803326 Differentielle Aktivierung Von C-fos Und Caspase-3 Im Hippocampal Neuronen Subpopulationen Nach Neonatale Hypoxie-Ischämie Journal of Neuroscience Research. Apr, 2008 | Pubmed ID: 18030677 BH3-only Proapoptotischen Bcl-2 Familie Mitglieder Noxa Und Puma Vermitteln Vorläufer Der Neuronalen Zelltod The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16822983 Interaktionen Zwischen Beta-Neuregulin Und Nervenwachstumsfaktoren in Motoneuron Apoptosis Journal of Neurochemistry. Apr, 2006 | Pubmed ID: 16524373 Neuregulin-Wachstumsfaktoren Und Ihrer ErbB-Rezeptoren Bilden Ein Potenzieller Signalling Netzwerk Für Schwannom Tumorentstehung Journal of Neuropathology and Experimental Neurology. Feb, 2006 | Pubmed ID: 16462207 Die Aktivierung Des Neuregulin-1/ErbB Signalwegs Fördert Die Proliferation Von Neoplastischen Schwann-Zellen in Der Menschlichen Malignen Peripheren Nervenscheidentumoren Oncogene. Aug, 2005 | Pubmed ID: 15897877 Neuregulin-1 Verbessert Das Überleben Der Menschlichen Astrozytären Gliomzellen Glia. Aug, 2005 | Pubmed ID: 15812817 Tumor-Suppressor-Mutationen Und Wachstumsfaktor Signalisierung in Der Pathogenese Der NF1-assoziierten Peripheren Nervenscheidentumore: III. Die Rolle Der Dysregulierte Wachstumsfaktor-Signalisierung Journal of Neuropathology and Experimental Neurology. Jan, 2005 | Pubmed ID: 15715079 Verbesserte Gentransfer in Neurogliazellen über Eine LWL-modifizierten Adenovirus-Vektor Biochemical and Biophysical Research Communications. Mar, 2005 | Pubmed ID: 15708001 Ganglion-spezifische Muster Von Diabetes-modulierte Genexpression in Prävertebralen Und Paravertebralen Sympathischen Ganglien Vor Der Entwicklung Von Neuroaxonalen Dystrophie Etabliert Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581182 Tumor-Suppressor-Mutationen Und Wachstumsfaktor Signalisierung in Der Pathogenese Der NF1-assoziierten Peripheren Nervenscheidentumore. I. Die Rolle Von Tumor-Suppressor-Mutationen Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581179 Neuregulin-1beta Induziert Neuriten Verlängerung Und Verzweigung in Kultivierten Hippocampus-Neuronen Molecular and Cellular Neurosciences. Dec, 2004 | Pubmed ID: 15555917 ErbB Transmembrane Tyrosinkinase-Rezeptoren Werden Von Sensorischen Und Motorischen Neuronen Hineinragenden Ischiasnerv Ausgedrückt The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2004 | Pubmed ID: 15385576 Konstitutive Aktivierung Des Neuregulin-1/erbB Signalwegs Fördert Die Proliferation Einer Humanen Peripheren Neuroepitheliom Zelllinie Journal of Neuro-oncology. Feb, 2004 | Pubmed ID: 15015657 Hypertrophe Und Malignen Peripheren Neuropathien Nervenscheidentumoren in Transgenen Mäusen überexprimiert Glialen Wachstumsfaktor Beta3 in Myelinisierenden Schwann-Zellen The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12917360 Konstitutiven Aktivierung Des Rezeptors Neuregulin-1/ErbB Signalweg Ist Essenziell Für Die Vermehrung Einer Neoplastischen Schwann-Zelllinie Glia. Aug, 2003 | Pubmed ID: 12838503 Lysophosphatidsäure Fördert Die Proliferation Von Adulten Schwann-Zellen Aus Axotomierten Ischiasnerv Isoliert Journal of Neuropathology and Experimental Neurology. May, 2003 | Pubmed ID: 12769191 Neuregulin-1 Verbessert Die Beweglichkeit Und Migration Von Humanen Astrozyten Gliomzellen The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12600989 Neuregulin-1 Und ErbB4 Immunreaktivität Mit Neuritischen Plaques Im Gehirn Alzheimer-Krankheit Und in Einem Transgenen Modell Der Alzheimer Krankheit Assoziiert Sind Journal of Neuropathology and Experimental Neurology. Jan, 2003 | Pubmed ID: 12528817 Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research Definition von Genfunktionen in der Tumorgenese durch Ex-vivo-Ablation von Flox-Allelen in bösartigen peripheren Nervenscheidentumorzellen Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research Orthotopen Xenografting of Human Luciferase-Tagged malignen peripheren Nervenscheide Tumorzellen für In vivo Prüfung von Kandidaten Therapeutika Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine
Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research
Definition von Genfunktionen in der Tumorgenese durch Ex-vivo-Ablation von Flox-Allelen in bösartigen peripheren Nervenscheidentumorzellen Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research
Orthotopen Xenografting of Human Luciferase-Tagged malignen peripheren Nervenscheide Tumorzellen für In vivo Prüfung von Kandidaten Therapeutika Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine