Steven L. Carroll Hollings Cancer Center Medical University of South Carolina Biography Publications Institution JoVE Articles Steven L. Carroll has not added a biography. If you are Steven L. Carroll and would like to personalize this page please email our Author Liaison for assistance. Publications Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival The American Journal of Pathology. Sep, 2023 | Pubmed ID: 37328102 LPAR1 and Aberrantly Expressed LPAR3 Differentially Promote the Migration and Proliferation of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Mar, 2023 | Pubmed ID: 36416236 Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table Biopreservation and Biobanking. Feb, 2023 | Pubmed ID: 35507966 Developmental, Neurochemical, and Behavioral Analyses of ErbB4 Cyt-1 Knockout Mice Journal of Neurochemistry. Jun, 2022 | Pubmed ID: 35523590 The RASopathies: Biology, Genetics and Therapeutic Options Advances in Cancer Research. 2022 | Pubmed ID: 35101235 Suppression of Fli-1 Protects Against Pericyte Loss and Cognitive Deficits in Alzheimer's Disease Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2022 | Pubmed ID: 35038582 R-Ras Subfamily Proteins Elicit Distinct Physiologic Effects and Phosphoproteome Alterations in Neurofibromin-null MPNST Cells Cell Communication and Signaling : CCS. Sep, 2021 | Pubmed ID: 34530870 The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change The American Journal of Pathology. Sep, 2021 | Pubmed ID: 34111428 The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33925820 Establishment and Genomic Characterization of a Sporadic Malignant Peripheral Nerve Sheath Tumor Cell Line Scientific Reports. Mar, 2021 | Pubmed ID: 33707600 Each Patient is a Research Biorepository: Informatics-enabled Research on Surplus Clinical Specimens Via the Living BioBank Journal of the American Medical Informatics Association : JAMIA. 01, 2021 | Pubmed ID: 33166379 Chemoembolizing Hepatocellular Carcinoma with Microsphere Cored with Arsenic Trioxide Microcrystal Drug Delivery. Nov, 2020 | Pubmed ID: 33307843 Assessing Interobserver Variability and Accuracy in the Histological Diagnosis and Classification of Cutaneous Neurofibromass Neuro-oncology Advances. Jul, 2020 | Pubmed ID: 32642737 Serum Pro-BDNF Levels Correlate with Phospho-tau Staining in Alzheimer's Disease Neurobiology of Aging. 03, 2020 | Pubmed ID: 31882186 Salinomycin Targets the Genome of Radioresistant Cells in Glioblastomas Neuro-oncology. 02, 2020 | Pubmed ID: 31784742 The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699905 Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia The American Journal of Pathology. 10, 2019 | Pubmed ID: 31351986 ErbB4 Promotes Malignant Peripheral Nerve Sheath Tumor Pathogenesis Via Ras-independent Mechanisms Cell Communication and Signaling : CCS. 07, 2019 | Pubmed ID: 31291965 The Evolution and Multi-molecular Properties of NF1 Cutaneous Neurofibromas Originating from C-fiber Sensory Endings and Terminal Schwann Cells at Normal Sites of Sensory Terminations in the Skin PloS One. 2019 | Pubmed ID: 31107888 Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia Journal of Neuropathology and Experimental Neurology. 04, 2019 | Pubmed ID: 30856249 Cutaneous Neurofibromas: Current Clinical and Pathologic Issues Neurology. 07, 2018 | Pubmed ID: 29987130 Oridonin Inhibits Aberrant AKT Activation in Breast Cancer Oncotarget. May, 2018 | Pubmed ID: 29844859 Pathology of NNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease Neuroscience. 08, 2018 | Pubmed ID: 29782905 Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms Advances in Anatomic Pathology. Sep, 2018 | Pubmed ID: 29762158 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve Journal of Neuropathology and Experimental Neurology. 04, 2017 | Pubmed ID: 28340093 BH3 Mimetics Suppress CXCL12 Expression in Human Malignant Peripheral Nerve Sheath Tumor Cells Oncotarget. Jan, 2017 | Pubmed ID: 28055968 Neuronal Exosomes Reveal Alzheimer's Disease Biomarkers in Down Syndrome Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27755974 Current Status and Recommendations for Biomarkers and Biobanking in Neurofibromatosis Neurology. Aug, 2016 | Pubmed ID: 27527649 STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells Molecular Cancer Research : MCR. 05, 2016 | Pubmed ID: 26883073 The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors As a Paradigm for Cross-Species Comparative Oncogenomics The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26740486 Classic Ras Proteins Promote Proliferation and Survival Via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells Journal of Neuropathology and Experimental Neurology. Jun, 2015 | Pubmed ID: 25946318 Combinatorial Therapy with Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289889 Varianti Genetiche Comuni in Loci CLDN2 E PRSS1-PRSS2 Alterano Rischio Per Pancreatite Alcol-correlati E Sporadica Nature Genetics. Nov, 2012 | Pubmed ID: 23143602 L'inibitore Di ErbB Pan PD168393 Migliora La Morte Apoptotica Indotta Da Disfunzione Lisosomiale Nelle Cellule Del Tumore Maligno Dei Nervi Periferici Guaina Neuro-oncology. Jan, 2012 | Pubmed ID: 22259051 Meccanismi Molecolari Promuovendo La Patogenesi Delle Neoplasie Delle Cellule Di Schwann Acta Neuropathologica. Dec, 2011 | Pubmed ID: 22160322 Modelli Murini Transgenici Gettano Nuova Luce Sulla Patogenesi Delle Neoplasie Neurofibromatosi Di Tipo I-correlati Del Sistema Nervoso Periferico Brain Research Bulletin. Aug, 2011 | Pubmed ID: 21855613 Varianti Comuni Presso MS4A4/MS4A6E, CD2AP, CD33 Ed EPHA1 Sono Associate Ad Esordio Tardivo Della Malattia Di Alzheimer Nature Genetics. May, 2011 | Pubmed ID: 21460841 Tamoxifen Inibisce La Crescita Di Tumori Maligni Dei Nervi Periferici Guaina in Maniera Indipendente Dal Recettore Estrogeno Neuro-oncology. Jan, 2011 | Pubmed ID: 21075781 Varianti Comuni Alle 7 P 21 Sono Associate a Degenerazione Lobare Frontotemporale Con Inclusioni TDP-43 Nature Genetics. Mar, 2010 | Pubmed ID: 20154673 Neuregulin-1 Beta and Neuregulin-1 Alpha Differentially Affect the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Nov, 2009 | Pubmed ID: 19306381 Come I Tumori Delle Cellule Di Schwann Lignaggio Forma NF1? Glia. Nov, 2008 | Pubmed ID: 18803326 Attivazione Differenziale Di C-fos E Caspase-3 in Sottopopolazioni Di Neuroni Hippocampal Dopo Ischemia-ipossia Neonatale Journal of Neuroscience Research. Apr, 2008 | Pubmed ID: 18030677 Membri Della Famiglia BH3-only Miselli Bcl-2 Noxa E Puma Mediano La Morte Delle Cellule Precursori Neurali The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16822983 Interazioni Tra Beta-neuregulina E Neurotrofine in Motor Neurone Apoptosis Journal of Neurochemistry. Apr, 2006 | Pubmed ID: 16524373 Neuregulina Fattori Di Crescita E Loro Recettori ErbB Formano Una Rete Di Segnalazione Potenziale Per Schwannoma Tumorigenesi Journal of Neuropathology and Experimental Neurology. Feb, 2006 | Pubmed ID: 16462207 Attivazione Della Via Di Segnalazione Di Neuregulina-1/ErbB Promuove La Proliferazione Delle Cellule Di Schwann Neoplastiche Tumori Guaina Umano Maligni Dei Nervi Periferici Oncogene. Aug, 2005 | Pubmed ID: 15897877 Neuregulina-1 Migliora La Sopravvivenza Delle Cellule Di Glioma Umano Astrocitari Glia. Aug, 2005 | Pubmed ID: 15812817 Mutazioni Soppressore Tumorale E Fattore Di Crescita Di Segnalazione Nella Patogenesi Dei Nervi Periferici Associati a NF1 Guaina Tumori: II. Il Ruolo Del Fattore Di Crescita Di Segnalazione Journal of Neuropathology and Experimental Neurology. Jan, 2005 | Pubmed ID: 15715079 Consegna Migliorata Gene in Cellule Neuroglial Utilizzando Un Vettore Di Fibra-modificato Adenovirus Biochemical and Biophysical Research Communications. Mar, 2005 | Pubmed ID: 15708001 Ganglio Specifici Pattern Di Espressione Genica Modulata Diabete Sono Stabiliti in Prevertebrale E Simpatico Gangli Paravertebrali Prima Dello Sviluppo Della Distrofia Neuroassonale Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581182 Mutazioni Soppressore Tumorale E Fattore Di Crescita Di Segnalazione Nella Patogenesi Di Tumori Guaina Dei Nervi Periferici Associati a NF1. I. Il Ruolo Di Mutazioni Soppressore Tumorale Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581179 Neuregulina-1beta Induce Estensione Dei Neuriti E Arborization in Neuroni Ippocampali Colti Molecular and Cellular Neurosciences. Dec, 2004 | Pubmed ID: 15555917 I Recettori Di ErbB Transmembrana Tirosina Chinasi Sono Espressi Dai Neuroni Sensoriali E Motori, Proiettando Nel Nervo Sciatico The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2004 | Pubmed ID: 15385576 Attivazione Costitutiva Della Via Di Segnalazione Di Neuregulina-1/erbB Promuove La Proliferazione Di Una Linea Cellulare Umana Neuroepitelioma Periferico Journal of Neuro-oncology. Feb, 2004 | Pubmed ID: 15015657 Neuropatie Ipertrofiche E Tumori Guaina Dei Nervi Periferici Maligni Nei Topi Transgenici Con Sovraesprimono Relativa Beta3 Di Fattore Di Crescita Gliale in Myelinating Cellule Di Schwann The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12917360 Attivazione Costitutiva Del Recettore Neuregulina-1/ErbB Signaling Pathway è Essenziale Per La Proliferazione Di Una Linea Neoplastica Delle Cellule Di Schwann Glia. Aug, 2003 | Pubmed ID: 12838503 Acido Lysophosphatidic Promuove La Proliferazione Delle Cellule Di Schwann Adulte Isolate Dal Nervo Sciatico Regenerativo Journal of Neuropathology and Experimental Neurology. May, 2003 | Pubmed ID: 12769191 Neuregulina-1 Migliora La Motilità E La Migrazione Delle Cellule Di Glioma Umano Astrocitari The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12600989 Immunoreattività Neuregulina-1 Ed ErbB4 è Associato Con Placche Nervosi Nel Cervello Di Malattia Di Alzheimer E in Un Modello Transgenico Della Malattia Di Alzheimer Journal of Neuropathology and Experimental Neurology. Jan, 2003 | Pubmed ID: 12528817 Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research Definizione delle funzioni geniche nella tumorigenesi mediante ablazione ex vivo di alleli floxed in cellule tumorali maligne della guaina del nervo periferico Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research Xenotrapianto ortotopico di Human-luciferasi con tag cellule maligne del tumore della guaina dei nervi periferici per In vivo Test di agenti terapeutici candidati Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine
Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research
Definizione delle funzioni geniche nella tumorigenesi mediante ablazione ex vivo di alleli floxed in cellule tumorali maligne della guaina del nervo periferico Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research
Xenotrapianto ortotopico di Human-luciferasi con tag cellule maligne del tumore della guaina dei nervi periferici per In vivo Test di agenti terapeutici candidati Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine
