Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors

August 25th, 2023

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Brittany Turner-Ivey¹, Jody Fromm Longo², Dorea P. Jenkins², Stephen T. Guest³, Steven L. Carroll^1,2

¹Hollings Cancer Center, Medical University of South Carolina, ²Department of Pathology and Laboratory Medicine, Medical University of South Carolina, ³Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor

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Wir haben einen speziesübergreifenden vergleichenden Onkogenomik-Ansatz entwickelt, der genomische Analysen und funktionelle genomische Screenings verwendet, um therapeutische Ziele in Tumoren, die in gentechnisch veränderten Mausmodellen auftreten, und den entsprechenden menschlichen Tumortyp zu identifizieren und zu vergleichen.

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Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors

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