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Understanding Tendon Impingement – Murine Explant Model for Studying Mechanobiology

December 8th, 2023
1,2, 1,2, 1,2,3, 1,2
1Department of Biomedical Engineering, University of Rochester, 2Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, 3Department of Pharmacology and Physiology, University of Rochester Medical Center

Summary
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我们提出了一个定制的实验平台和组织培养方案，该方案以持续的细胞活力再现了由小鼠后肢外植体中跟腱插入撞击驱动的纤维软骨变化，提供了一个适合探索肌腱撞击的机制生物学的模型。

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