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Visualisering af Mitokondriel Respiratorisk funktion ved hjælp af cytochrom C Oxidase / succinat dehydrogenase (COX / SDH) Dobbelt-mærkning Histochemistry
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Visualisering af Mitokondriel Respiratorisk funktion ved hjælp af cytochrom C Oxidase / succinat dehydrogenase (COX / SDH) Dobbelt-mærkning Histochemistry

Article DOI: 10.3791/3266-v • 06:54 min • November 23rd, 2011
November 23rd, 2011 •
1,2
1Department of Neuroscience, Karolinska Institutet, 2National Institute on Drug Abuse (NIDA)

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Cytochrom c oxidase / natrium dehydrogenase (COX / SDH) double-mærkning metode giver mulighed for direkte visualisering af mitokondrie respiratoriske enzym mangler i fersk-frosne vævssnit. Dette er en ligetil histokemiske teknik og er nyttig i at undersøge mitokondrie-sygdomme, aldring og aldersrelaterede sygdomme.

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Cellebiologi aldring hjerne COX / SDH histochemistry mitochondrier mitokondrier sygdom mitokondriel dysfunktion mtDNA mtDNA mutationer respiratorisk kæde
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