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Journal / Cancer Research / 单壁碳纳米管 (sscnt) (mallat1 反义寡 3号)…
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JoVE Journal Cancer Research
单壁碳纳米管 (sscnt) (mallat1 反义寡 3号) 抑制多骨髓瘤细胞在体内的生长
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单壁碳纳米管 (sscnt) (mallat1 反义寡 3号) 抑制多骨髓瘤细胞在体内的生长

Article DOI: 10.3791/58598-v • 07:24 min • December 13th, 2018
December 13th, 2018 •
*1,2, *1, 1
1Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, 2Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School
* These authors contributed equally

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这篇手稿描述了单壁碳纳米管 (swcnt)-共轭 malat1 反义 gapgmer dna 寡核苷酸 (swcnt 反材料-malat1) 的合成, 这表明了 swcnt 的可靠交付和强大的治疗效果。抗马拉特1在体外和体内。介绍了用于 swcnt 抗 malat1 的合成、改性、共轭和注射的方法。

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癌症研究 第142期 单壁碳纳米管 lncRNA 多发性骨髓瘤 malat1 长非编码 rna lncrna
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