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JoVE Journal Neuroscience
Vurdering af langvarig depression induktion i voksne cerebellar skiver
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Vurdering af langvarig depression induktion i voksne cerebellar skiver

Article DOI: 10.3791/59859-v • 09:30 min • October 16th, 2019
October 16th, 2019 •
1, 2
1Laboratory for Behavioral Genetics, Center for Brain Science, RIKEN, 2Senior Adviser's Office, Center for Brain Science, RIKEN

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I nogle genmanipulerede dyr, ved hjælp af en enkelt protokol kan undlade at fremkalde LTD i cerebellar Purkinje celler, og der kan være en uoverensstemmelse mellem LTD og motor læring. Flere protokoller er nødvendige for at vurdere LTD-induktion i genmanipulerede dyr. Standard protokoller vises.

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Neurovidenskab synaptisk plasticitet LTD hjerne skive hel-celle optagelse mus Purkinje celle cerebellum parallel fiber klatring fiber
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