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In Vivo Targeting di cellule tumorali umane Xenografted con nanoparticelle di silice fluorescenti funzionalizzate nel pesce zebra

Article DOI: 10.3791/61187-v • 10:26 min • May 8th, 2020
May 8th, 2020 •
*1, *1, 2, 1, 2,3,4, 1
1Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Cancer Research Center, Boston University School of Medicine, 2Department of Biomedical Engineering, Tufts University, 3Department of Mechanical Engineering, Tufts University, 4Department of Physics, Tufts University
* These authors contributed equally

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Descritto qui è un metodo per utilizzare gli embrioni di pesce zebra per studiare la capacità delle nanoparticelle funzionalizzate di colpire le cellule tumorali umane in vivo. Questo metodo consente la valutazione e la selezione di nanoparticelle ottimali per test futuri su animali di grandi dimensioni e in studi clinici.

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Ricerca sul cancro Numero 159 Pesce zebra Casper trapianto targeting in vivo nanoparticelle cancro
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