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Implantation af human størrelse koronar stenter i Rat Abdominal Aorta Ved hjælp af en Trans-Femoral Access
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Implantation af human størrelse koronar stenter i Rat Abdominal Aorta Ved hjælp af en Trans-Femoral Access

Article DOI: 10.3791/61442-v • 05:04 min • November 19th, 2020
November 19th, 2020 •
*1, *1, 1, 1, 1, *1,2,3, *1
1Division of Cardiology, Angiology, and Critical Care, University Hospital RWTH Aachen, 2Department for Operative Intensive Medicine, University Hospital RWTH Aachen, 3Institute for Pathology "Victor Babes"
* These authors contributed equally

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Denne protokol beskriver implantationen af menneskelige koronar stenter i abdominal aorta af rotter med en apoE-/- baggrund ved hjælp af en trans-femoral adgang. Sammenlignet med andre dyremodeller bærer murinmodeller fordelene ved høj gennemløb, reproducerbarhed, nem håndtering og boliger og en bred tilgængelighed af molekylære markører.

Tags

Medicin Problem 165 Koronar stent apolipoprotein E-mangelfulde rotter restenosis neointimal hyperplasi dyremodel zink-finger nuklease trans-femoral adgang
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