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Implantação de stents coronários de tamanho humano na aorta abdominal de rato usando um acesso trans-femoral
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Implantação de stents coronários de tamanho humano na aorta abdominal de rato usando um acesso trans-femoral

Article DOI: 10.3791/61442-v • 05:04 min • November 19th, 2020
November 19th, 2020 •
*1, *1, 1, 1, 1, *1,2,3, *1
1Division of Cardiology, Angiology, and Critical Care, University Hospital RWTH Aachen, 2Department for Operative Intensive Medicine, University Hospital RWTH Aachen, 3Institute for Pathology "Victor Babes"
* These authors contributed equally

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Este protocolo descreve a implantação de stents coronários humanos na aorta abdominal de ratos com um apoE-/- fundo usando um acesso trans-femoral. Em comparação com outros modelos animais, os modelos murinos carregam as vantagens da alta produtividade, reprodutibilidade, facilidade de manuseio e habitação, e uma ampla disponibilidade de marcadores moleculares.

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Medicina Edição 165 Stent Coronário apolipoproteína E-deficientes ratos restenosis hiperplasia neointimal modelo animal nuclease de dedo de zinco acesso trans-femoral
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