JoVE Journal
Neuroscience
Neuroscience
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
Summary
Please note that all translations are automatically generated.
传统的光血栓中风 (PTS) 模型主要诱导对组织纤溶酶原激活剂 (tPA) 溶解治疗具有高耐药性的致密血小板聚集体。本文通过共注射凝血酶和光敏染料进行光活化,引入了改良的小鼠PTS模型。凝血酶增强的 PTS 模型产生混合血小板:纤维蛋白凝块,并且对 tPA 溶栓高度敏感。