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Immunology and Infection

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JoVE Journal Immunology and Infection
Terapeutisk evaluering af fækal mikrobiotatransplantation i en Interleukin 10-mangelfuld musemodel
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Terapeutisk evaluering af fækal mikrobiotatransplantation i en Interleukin 10-mangelfuld musemodel

Article DOI: 10.3791/63350-v • 05:41 min • April 6th, 2022
April 6th, 2022 •
1,2, 1, 2, 1
1Division of Gastroenterology, Department of Internal Medicine, University of Texas Medical Branch at Galveston, 2Department of Gastroenterology, Xiangya Hospital of Central South University

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Samspillet mellem genetisk modtagelighed, slimhindeimmunitet og intestinalt mikroøkologisk miljø er involveret i patogenesen af inflammatorisk tarmsygdom (IBD). I denne undersøgelse anvendte vi fækal mikrobiotatransplantation til IL-10-mangelfulde mus og undersøgte dens indvirkning på tyktarmsbetændelse og hjertefunktion.

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Immunologi og infektion udgave 182 inflammatorisk tarmsygdom fækal mikrobiotatransplantation ulcerøs colitis Crohns sygdom dysbiose interleukin 10
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