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Journal / Immunology and Infection / Canine intestinale organoïden in een tweekamer…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Canine intestinale organoïden in een tweekamer permeabel ondersteuningssysteem
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Canine intestinale organoïden in een tweekamer permeabel ondersteuningssysteem

Article DOI: 10.3791/63612-v • 11:11 min • March 2nd, 2022
March 2nd, 2022 •
1, 1, 2, 3, 2, 3, 4, 5, 2, 2,3, 1,3
1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 33D Health Solutions Inc., 4Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Food and Drug Administration, 5Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration

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Hier presenteren we een protocol dat de cultuur van canine intestinale organoïden beschrijft in een tweekamerig, permeabel ondersteuningssysteem. Organoïde zaaien in de doorlatende steunen, het onderhoud van de monolaag en de daaropvolgende experimenten met de permeabiliteit van geneesmiddelen worden beschreven.

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Immunologie en infectie Uitgave 181 Doorlaatbare ondersteuning Dubbele kamer Hond Organoïde Darm Stamcel Translationeel onderzoek Omgekeerd translationeel onderzoek One Health Initiative Geneesmiddelontdekking Geneesmiddeldoorlaatbaarheid
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