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JoVE Journal Medicine

Гетеротопная модель мыши для изучения трансплантации гортани

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Journal (Medicine)

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Journal (Medicine)

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Гетеротопная модель мыши для изучения трансплантации гортани

Article DOI: 10.3791/63619-v • 14:15 min • January 13th, 2023

January 13th, 2023 •

Maeve M. Kennedy*¹, Egehan Salepci*^1,2, Cheryl Myers¹, Marshall Strome^3,4, David G. Lott^1,5

¹Head and Neck Regenerative Medicine Laboratory, Center for Regenerative Medicine, Mayo Clinic Arizona, ²Department of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, ³Department of Otolaryngology, Vanderbilt University, ⁴Cleveland Clinic Head and Neck Institute, ⁵Division of Laryngology, Department of Otolaryngology Head and Neck Surgery, Mayo Clinic Arizona

* These authors contributed equally

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Целью этой рукописи является описание микрохирургических этапов, необходимых для выполнения гетеротопной трансплантации гортани у мышей. Преимуществами этой мышиной модели по сравнению с другими животными моделями трансплантации гортани являются ее экономическая эффективность и доступность иммунологических анализов и данных.

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