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Dekryptering af 3D-kromatinorganisation med høj opløsning via Capture Hi-C
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Dekryptering af 3D-kromatinorganisation med høj opløsning via Capture Hi-C

Article DOI: 10.3791/64166-v • 09:32 min • October 14th, 2022
October 14th, 2022 •
1, 1, 2, 1, 3, 4, 1, 1,5
1EMBL: European Molecular Biology Laboratory, 2Institut Curie, 3Agilent Technologies, 4Genmab BV, 5Collège de France

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Denne protokol beskriver Capture Hi-C-metoden, der bruges til at karakterisere 3D-organiseringen af megabaserede målrettede genomiske regioner ved høj opløsning, herunder grænser for topologisk associerende domæner (TAD'er) og langtrækkende kromatininteraktioner mellem regulatoriske og andre DNA-sekvenselementer.

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Tilbagetrækning nr. 188
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