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JoVE Journal Cancer Research
Modellering av hjernemetastase ved intern karotisarterieinjeksjon av kreftceller
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Modellering av hjernemetastase ved intern karotisarterieinjeksjon av kreftceller

Article DOI: 10.3791/64216-v • 10:01 min • August 2nd, 2022
August 2nd, 2022 •
1, 2, 1, 3, 2, *1,4, *1,5
1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital
* These authors contributed equally

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Hjernemetastase er en årsak til alvorlig sykelighet og dødelighet hos kreftpasienter. De fleste musemodeller for hjernemetastaser kompliseres av systemiske metastaser som forvirrer analyse av dødelighet og terapeutiske intervensjonsutfall. Presentert her er en protokoll for intern carotisinjeksjon av kreftceller som produserer konsistente intrakraniale svulster med minimale systemiske svulster.

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Kreftforskning utgave 186
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