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用于癌症表观遗传学研究的ATAC-Seq优化
 
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用于癌症表观遗传学研究的ATAC-Seq优化

Article DOI: 10.3791/64242-v 07:13 min June 30th, 2022
June 30th, 2022

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Summary

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Click here for the English version.

ATAC-seq是一种DNA测序方法,它使用过度活跃的突变转座酶Tn5来绘制由转录因子介导的染色质可及性的变化。ATAC-seq能够发现癌细胞表型改变的分子机制。该协议概述了上皮细胞类型(包括癌细胞)中ATAC-seq的优化程序。

Tags

癌症研究,第184期,染色质可及性,转座酶,调控元件,基因表达,癌症表观遗传学
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