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Journal / Cancer Research / Pankreas Kanserini Modellemek için Sinjenik Fare…
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Cancer Research

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JoVE Journal Cancer Research
Pankreas Kanserini Modellemek için Sinjenik Fare Ortotopik Allogreftleri
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Pankreas Kanserini Modellemek için Sinjenik Fare Ortotopik Allogreftleri

Article DOI: 10.3791/64253-v • 06:20 min • October 4th, 2022
October 4th, 2022 •
1,2,3, 1,2,3,4, *1,2,3, *1,2,3
1Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 2Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 3Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, 4Department of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich
* These authors contributed equally

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Pankreatik duktal adenokarsinomun (PDAC) sinjenik fare ortotopik allogreftleri, hastalık alt tiplerinin biyolojisini, fenotiplerini ve terapötik yanıtlarını özetler. Hızlı, tekrarlanabilir tümör progresyonları nedeniyle, preklinik çalışmalarda yaygın olarak kullanılmaktadırlar. Burada, pankreasa sinjenik murin PDAC kültürleri enjekte ederek bu modelleri oluşturmak için ortak uygulamalar gösteriyoruz.

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Kanser Araştırmaları Sayı 188 Pankreas ortotopik implantasyon allogreft pankreatik duktal adenokarsinom tümör mikroçevresi tedavi
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